Reliability of brain volume measures of accelerated 3D T1-weighted images with deep learning-based reconstruction.

Purpose: The time-intensive nature of acquiring 3D T1-weighted MRI and analyzing brain volumetry limits quantitative evaluation of brain atrophy. We explore the feasibility and reliability of deep learning-based accelerated MRI scans for brain volumetry. Methods: This retrospective study collected 3...

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Publicado en:Neuroradiology Vol. 67; no. 1; pp. 171 - 183
Autores principales: Jung, Woojin, Jeong, Geunu, Kim, Sohyun, Hwang, Inpyeong, Choi, Seung Hong, Jeon, Young Hun, Choi, Kyu Sung, Lee, Ji Ye, Yoo, Roh-Eul, Yun, Tae Jin, Kang, Koung Mi
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jan2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2025
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      pub: Springer Nature
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        10.1007/s00234-024-03461-5
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        atl: Reliability of brain volume measures of accelerated 3D T1-weighted images with deep learning-based reconstruction.
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          Jung, Woojin
          Jeong, Geunu
          Kim, Sohyun
          Hwang, Inpyeong
          Choi, Seung Hong
          Jeon, Young Hun
          Choi, Kyu Sung
          Lee, Ji Ye
          Yoo, Roh-Eul
          Yun, Tae Jin
          Kang, Koung Mi
        affil: AIRS Medical, 223, Teheran-ro, Gangnam-gu, 06142, Seoul, Republic of Korea
      sug:
        subj:
          Brain Radiography
          Magnetic Resonance Imaging Methods
          Imaging, Three-Dimensional Methods
          Image Interpretation, Computer Assisted
          Deep Learning
          Radiographic Image Enhancement
          Reliability
          Human
          Male
          Female
          Middle Age
          Aged
          Retrospective Design
          Record Review
          Validation Studies
          Intraclass Correlation Coefficient
          Linear Regression
          Descriptive Statistics
          Funding Source
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: The time-intensive nature of acquiring 3D T1-weighted MRI and analyzing brain volumetry limits quantitative evaluation of brain atrophy. We explore the feasibility and reliability of deep learning-based accelerated MRI scans for brain volumetry. Methods: This retrospective study collected 3D T1-weighted data using 3T from 42 participants for the simulated acceleration dataset and 48 for the validation dataset. The simulated acceleration dataset consists of three sets at different simulated acceleration levels (Simul-Accel) corresponding to level 1 (65% undersampling), 2 (70%), and 3 (75%). These images were then subjected to deep learning-based reconstruction (Simul-Accel-DL). Conventional images (Conv) without acceleration and DL were set as the reference. In the validation dataset, DICOM images were collected from Conv and accelerated scan with DL-based reconstruction (Accel-DL). The image quality of Simul-Accel-DL was evaluated using quantitative error metrics. Volumetric measurements were evaluated using intraclass correlation coefficients (ICCs) and linear regression analysis in both datasets. The volumes were estimated by two software, NeuroQuant and DeepBrain. Results: Simul-Accel-DL across all acceleration levels revealed comparable or better error metrics than Simul-Accel. In the simulated acceleration dataset, ICCs between Conv and Simul-Accel-DL in all ROIs exceeded 0.90 for volumes and 0.77 for normative percentiles at all acceleration levels. In the validation dataset, ICCs for volumes > 0.96, ICCs for normative percentiles > 0.89, and R2 > 0.93 at all ROIs except pallidum demonstrated good agreement in both software. Conclusion: DL-based reconstruction achieves clinical feasibility of 3D T1 brain volumetric MRI by up to 75% acceleration relative to full-sampled acquisition.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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