The Developmental Autism Early Screening (DAES): A Novel Test for Screening Autism Spectrum Disorder.
This study was undertaken to set a novel developmental screening test for autism spectrum disorder (ASD) using the Griffiths Scales of Child Development (Griffith III) (Green et al., 2016; Stroud et al., 2016), in order to intercept the early atypical developmental patterns indicating ASD risk in th...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 55; no. 1; pp. 221 - 237 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jan2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182844505&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182844505 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Jan2025 vid: 55 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 182844505 174285556 182844505 182844505 10.1007/s10803-023-06184-3 182844505 ppf: 221 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The Developmental Autism Early Screening (DAES): A Novel Test for Screening Autism Spectrum Disorder. aug: au: Cirnigliaro, Lara Valle, Maria Stella Casabona, Antonino Randazzo, Martina La Bruna, Francesca Pettinato, Fabio Narzisi, Antonio Rizzo, Renata Barone, Rita affil: https://ror.org/03a64bh57 Child Neurology and Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Policlinico Via Santa Sofia, 78, 95123, Catania, Italy sug: subj: Autism Spectrum Disorder Diagnosis Health Screening In Infancy and Childhood Scales Child Development Autism Spectrum Disorder Risk Factors Risk Assessment Developmental Disabilities Children with Disabilities Early Diagnosis Human Italy Male Female Sensitivity and Specificity Predictive Value of Tests Infant Child Infant: 1-23 months Child: 6-12 years Male Female ab: This study was undertaken to set a novel developmental screening test for autism spectrum disorder (ASD) using the Griffiths Scales of Child Development (Griffith III) (Green et al., 2016; Stroud et al., 2016), in order to intercept the early atypical developmental patterns indicating ASD risk in the first 3 years of age. An observational and interactive ASD screener, the Developmental Autism Early Screening (DAES), was developed by detecting Griffiths III items differentiating toddlers with ASD risk from those with global developmental delay (DD) or neurotypical development. The DAES was validated with ASD-specific diagnostic instruments (ADOS-2) and the cut-off score based on sensitivity, specificity and positive predictive value that best differentiates between ASD and non-ASD children was identified. We enrolled a total sample of 297 subjects, including children at risk for ASD or DD and neurotypical children. At a cut-off score of 12.5, the DAES had a sensitivity of 93%, specificity of 98.4%, positive predictive value of 96.3% and negative predictive value of 96.9% for identifying children at risk for ASD from non-ASD participants (DD/neurotypical children). The DAES total score correlated significantly with the ADOS-2 calibrated severity scores (CSS) (R = 0.53, p < 0.001). Three ASD risk ranges were identified according to DAES total and ADOS-2 CSS: Little-to-no risk (CSS: 1–3, DAES: 1–7); Mild-to-moderate risk (CSS: 4–5, DAES: 8–14); Moderate-to-severe risk (CSS: 6–10, DAES ≥ 15). The DAES provides a direct approach based on developmental profiles to stratify risk for ASD in early childhood ensuring at risk children the most appropriate diagnostic procedures and targeted intervention. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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