Refractory pyoderma gangrenosum-like ulcerations in granulomatosis with polyangiitis treated successfully with rituximab.
Granulomatosis with polyangiitis (GPA) is a small-to- medium vessel vasculitis that can affect the skin, respiratory tract, kidneys and other organs. A rare cutaneous manifestation of GPA is pyoderma gangrenosum (PG)-like ulcerations, which can have debilitating and disfiguring consequences. We repo...
| Publicado en: | BMJ Case Reports Vol. 18; no. 1; pp. 1 - 4 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
BMJ Publishing Group
Jan2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=182860278&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 182860278 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1757790X B755 jtl: BMJ Case Reports issn: 1757790X maglogo: N pubinfo: dt: Jan2025 vid: 18 iid: 1 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 182860278 10.1136/bcr-2024-262584 182860278 ppf: 1 ppct: 3 formats: tig: atl: Refractory pyoderma gangrenosum-like ulcerations in granulomatosis with polyangiitis treated successfully with rituximab. aug: au: Tran, Vanessa Chatfield, Simon Ramirez, Ann Scardamaglia, Laura affil: Dermatology, The Royal Melbourne Hospital, Parkville, Victoria, Australia. sug: ab: Granulomatosis with polyangiitis (GPA) is a small-to- medium vessel vasculitis that can affect the skin, respiratory tract, kidneys and other organs. A rare cutaneous manifestation of GPA is pyoderma gangrenosum (PG)-like ulcerations, which can have debilitating and disfiguring consequences. We report the case of a man in his 40s with refractory PG-like ulcerations secondary to GPA, not responsive to conventional immunosuppression, who was successfully treated with rituximab. This case emphasises the need for early recognition of this rare manifestation to allow for prompt initiation of treatment. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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