Evaluation of Human Papillomavirus Vaccination and Cancer Prevention Behaviors among LGBTQI + Individuals: A Cross-Sectional Study.

Human Papillomavirus (HPV) vaccination and cervical cancer screening rates are suboptimal in the US, particularly among historically underserved groups like Lesbian, Gay, Bisexual, Transgender, Queer, and Intersex (LGBTQI+)-identifying women and transgender men. Therefore, our cross-sectional study...

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Published in:Journal of Community Health Vol. 50; no. 1; pp. 98 - 111
Main Authors: Rana, Sanjana K., Perkins, Rebecca B., Carr, Devan, Feldman, Sarah, Welch, Kelly, Duffey-Lind, Eileen, Villa, Alessandro
Format: Article
Published: Springer Nature Feb2025
Subjects:
Online Access:View this record in EBSCOhost
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      dt: Feb2025
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      pub: Springer Nature
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        10.1007/s10900-024-01401-1
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        atl: Evaluation of Human Papillomavirus Vaccination and Cancer Prevention Behaviors among LGBTQI + Individuals: A Cross-Sectional Study.
      aug:
        au:
          Rana, Sanjana K.
          Perkins, Rebecca B.
          Carr, Devan
          Feldman, Sarah
          Welch, Kelly
          Duffey-Lind, Eileen
          Villa, Alessandro
        affil:
          Team Maureen, North Falmouth, MA, USA
          https://ror.org/05qwgg493 Department of Obstetrics and Gynecology, Boston University Chobanian and Avdesian School of Medicine and Boston Medical Center Cancer Center, Boston, MA, USA
          https://ror.org/02jzgtq86 Community Benefits Office, Dana-Farber Cancer Institute, Boston, MA, USA
          https://ror.org/03vek6s52 Division of Gynecologic Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
          https://ror.org/02jzgtq86 Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
          https://ror.org/00v47pv90 Oral Medicine, Oral Oncology and Dentistry, Miami Cancer Institute, Baptist Health South Florida, 8900 North Kendall Drive, 33176, Miami, FL, USA
      su:
        Immunization
        Cross-sectional method
        Gender identity
        Insurance
        LGBTQ+ people
        Papillomavirus diseases
        Cervix uteri tumors
        Research funding
        Early detection of cancer
        Human papillomavirus vaccines
        Descriptive statistics
        Odds ratio
        Confidence intervals
        Gynecologic examination
        Vaccination status
      sug:
        subj:
          Immunization
          Cross-sectional method
          Gender identity
          Insurance
          LGBTQ+ people
          Other Insurance Funds
          Third Party Administration of Insurance and Pension Funds
          All Other Insurance Related Activities
          Papillomavirus diseases
          Cervix uteri tumors
          Research funding
          Early detection of cancer
          Human papillomavirus vaccines
          Descriptive statistics
          Odds ratio
          Confidence intervals
          Gynecologic examination
          Vaccination status
      keyword:
        Cancer screening
        Human papillomavirus
        LGBTQI+
        Medical and Health Sciences Public Health and Health Services
        Vaccine
        Cancer screening
        Human papillomavirus
        LGBTQI+
        Medical and Health Sciences Public Health and Health Services
        Vaccine
      ab: Human Papillomavirus (HPV) vaccination and cervical cancer screening rates are suboptimal in the US, particularly among historically underserved groups like Lesbian, Gay, Bisexual, Transgender, Queer, and Intersex (LGBTQI+)-identifying women and transgender men. Therefore, our cross-sectional study assessed factors associated with these rates among LGBTQI+-identifying women and transgender men. HPV-related cancer knowledge, HPV vaccination and cervical cancer screening status, and the acceptability of self-collection for screening of 1983 LGBTQI+-identifying women and transgender men was assessed via an online survey available to members of the HER mobile app from March to May 2022. Associations between sociodemographic factors, vaccination, and screening were assessed using multivariable logistic regressions from November 2022 to December 2023. Most participants aged 18–26 (77.0%) and 6.3% of participants aged ≥46 (P < 0.001) had received at least one dose of the HPV vaccine. Cervical cancer screening rates were positively associated with age: 70.5% of those aged 21–26 and 96.1% aged ≥46 (P < 0.001). Screening was negatively associated with male gender identity (OR, 0.13; 95% CI, 0.04–0.42; P < 0.001), being uninsured (OR, 0.40; 95% CI, 0.24–0.67; P < 0.001), and being unvaccinated against HPV (OR, 0.28; 95% CI, 0.18–0.43; P < 0.001). 29.6% of those unscreened believed screening was not needed, and 22.1% were uncomfortable with pelvic exams. 40.4% of all participants would prefer self-collection for screening. Our findings indicate opportunities to increase screening and vaccination. Among under-screened individuals, lack of knowledge about screening necessity and discomfort with pelvic exams were important barriers. Targeted interventions addressing patient knowledge, practitioner communication, and exploring self-screening strategies are warranted.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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