The amygdala volume moderates the relationship between childhood maltreatment and callous-unemotional traits in adolescents with conduct disorder.

CU traits, characterized by shallow affect, lack of fear, and absence of remorse, have been moderately associated with childhood maltreatment in a recent meta-analysis. However, the potential impact of brain structures remains undetermined. This paper examines the relationship between callous-unemot...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 1; pp. 205 - 215
Autores principales: Jiang, Yali, Gao, Yidian, Dong, Daifeng, Sun, Xiaoqiang, Situ, Weijun, Yao, Shuqiao
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jan2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: The amygdala volume moderates the relationship between childhood maltreatment and callous-unemotional traits in adolescents with conduct disorder.
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        au:
          Jiang, Yali
          Gao, Yidian
          Dong, Daifeng
          Sun, Xiaoqiang
          Situ, Weijun
          Yao, Shuqiao
        affil: https://ror.org/053w1zy07 Department of Psychology, School of Education Science, Hunan Normal University, Changsha, People's Republic of China
      sug:
        subj:
          Child Behavior Disorders Psychosocial Factors
          Child Abuse Psychosocial Factors
          Emotions Evaluation
          Amygdala
          Human
          Male
          Female
          Adolescence
          Child
          Social Behavior
          Personality
          Aggression
          China
          Academic Medical Centers China
          Questionnaires
          Psychiatrists
          Self Report
          Descriptive Statistics
          Comparative Studies
          Data Analysis Software
          Analysis of Covariance
          Magnetic Resonance Imaging
          Funding Source
          Adolescent: 13-18 years
          Child: 6-12 years
          Male
          Female
      ab: CU traits, characterized by shallow affect, lack of fear, and absence of remorse, have been moderately associated with childhood maltreatment in a recent meta-analysis. However, the potential impact of brain structures remains undetermined. This paper examines the relationship between callous-unemotional (CU) traits, childhood maltreatment, and amygdala volumes. In this study, we used a region-of-interest (ROI) analysis to explore the interaction between the volumes of the amygdala, childhood maltreatment, and the manifestation of CU traits in adolescents diagnosed with conduct disorder (CD, N = 67), along with a comparison group of healthy-control youths (HCs, N = 89). The ROI analysis revealed no significant group differences in the bilateral amygdalar volumes. Significant positive correlation was discovered between all forms of child maltreatment (except for physical neglect) and CU traits across subjects. But the interaction of physical abuse and amygdala volumes was only significant within CD patients. Notably, a sensitivity analysis suggested that gender significantly influences these findings. These results contribute critical insights into the etiology of CU traits, emphasizing the need for customized clinical assessment tools and intervention strategies.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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