Attention-deficit/hyperactivity disorder and subsequent diagnoses of major psychiatric disorders: a nationwide population-based study.

We evaluated the risk of being diagnosed with various psychiatric disorders after an attention-deficit/hyperactivity disorder (ADHD) diagnosis using data from South Korea's National Health Insurance Service from 2002 to 2019, which covers approximately 97% of the country's population. ADHD and contr...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 1; pp. 315 - 327
Autores principales: Kim, Sujin, Kim, Mi-Sook, Kim, Jinhee, Kim, Jae Sung, Hong, Soon-Beom
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jan2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-024-02497-5
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        atl: Attention-deficit/hyperactivity disorder and subsequent diagnoses of major psychiatric disorders: a nationwide population-based study.
      aug:
        au:
          Kim, Sujin
          Kim, Mi-Sook
          Kim, Jinhee
          Kim, Jae Sung
          Hong, Soon-Beom
        affil: https://ror.org/01z4nnt86 Department of Psychiatry, Seoul National University Hospital, Seoul, Korea
      sug:
        subj:
          Attention Deficit Hyperactivity Disorder Complications
          Psychotic Disorders Risk Factors
          Risk Assessment
          Comorbidity
          Psychotic Disorders Epidemiology
          Human
          Funding Source
          South Korea
          Male
          Female
          Child
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Population-Based Case Control
          Descriptive Statistics
          Data Analysis Software
          Chi Square Test
          Confidence Intervals
          Probability
          Depression Risk Factors
          Bipolar Disorder Risk Factors
          Schizophrenia Risk Factors
          Tic Risk Factors
          Age of Onset
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: We evaluated the risk of being diagnosed with various psychiatric disorders after an attention-deficit/hyperactivity disorder (ADHD) diagnosis using data from South Korea's National Health Insurance Service from 2002 to 2019, which covers approximately 97% of the country's population. ADHD and control groups were selected after propensity score matching was performed for individuals diagnosed with ADHD and their age- and sex-matched counterparts from the general population. Comorbid psychiatric disorders included depressive disorder, bipolar disorder, tic disorder, and schizophrenia. The incidence of newly diagnosed psychiatric disorders was compared between the groups. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated and adjusted for ADHD medication prescription. After matching, 353,898 individuals were assigned to each of the two groups. Compared to the control group, the ADHD group showed a significantly higher risk of being subsequently diagnosed with depressive disorder, bipolar disorder, schizophrenia, and tic disorder. The onset age of depressive disorder, bipolar disorder, and schizophrenia in the ADHD group was 16–17 years, approximately 5 years earlier than that in the control group. The risk for depression was the highest in individuals with high income levels, and that for schizophrenia was the highest among rural patients. The median length of the follow-up time until the diagnosis of each comorbid psychiatric disorder was 7.53, 8.43, 8.53, and 8.34 years for depressive disorder, bipolar disorder, schizophrenia, and tic disorder, respectively. Individuals with ADHD had an overall higher risk of being diagnosed with subsequent psychiatric disorders than did the controls. Hence, they should be carefully screened for other psychiatric symptoms from an early age and followed up for an extended duration, along with appropriate interventions for ADHD symptoms, including psychosocial treatments and educational approaches.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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