Mortality Prediction in Patients With Breast Cancer by Artificial Neural Network Model and Elastic Net Regression.
Background: Breast cancer (BC) is the most common cancer in women, and it is important to identify models that can accurately predict mortality in patients with this cancer. The aim of the present study was to use the elastic net regression and artificial neural network (ANN) models in diagnosing an...
| Publicado en: | Journal of Research in Health Sciences Vol. 25; no. 1; pp. 1 - 8 |
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| Autores principales: | , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Hamadan University of Medical Sciences, School of Public Health
Winter2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183064768&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183064768 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 22287795 903Q jtl: Journal of Research in Health Sciences issn: 22287795 maglogo: N pubinfo: dt: Winter2025 vid: 25 iid: 1 pid: 54266 pub: Hamadan University of Medical Sciences, School of Public Health artinfo: ui: 183064768 183064768 183064768 10.34172/jrhs.2025.173 183064768 ppf: 1 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Mortality Prediction in Patients With Breast Cancer by Artificial Neural Network Model and Elastic Net Regression. aug: au: Esmaeili, Anis Karamoozian, Ali Bahrampour, Abbas affil: Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran sug: subj: Breast Neoplasms Mortality Mortality Risk Factors Risk Assessment Neural Networks (Computer) Prediction Models Human Adult Middle Age Aged Iran Cross Sectional Studies Sensitivity and Specificity Prediction Algorithms Descriptive Statistics Comparative Studies Regression ROC Curve Cancer Patients Female Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Female ab: Background: Breast cancer (BC) is the most common cancer in women, and it is important to identify models that can accurately predict mortality in patients with this cancer. The aim of the present study was to use the elastic net regression and artificial neural network (ANN) models in diagnosing and predicting factors affecting BC mortality. Study Design: A cross-sectional study. Methods: The data of 2,836 people with BC during 2014-2018 were analyzed in this study. Information was registered in the cancer registration system of Kerman University of Medical Sciences. Death status was considered the dependent variable, while age, morphology, tumor differentiation, residence status, and residence place were regarded as independent variables. Sensitivity, specificity, accuracy, area under the receiver operating characteristic curve (AUC), precision, and F1-score were used to compare the models. Results: Based on the test set, the elastic net regression determined factors affecting BC mortality (with sensitivity of 0.631, specificity of 0.814, AUC of 0.629, accuracy of 0.792, precision of 0.318, and F1-score of 0.42) and ANN did so (with sensitivity of 0.66, specificity of 0.748, AUC of 0.704, accuracy of 0.738, precision of 0.265, and F1-score of 0.37). Conclusion: The sensitivity and AUC of the ANN model were higher than those of the elastic net regression, but the specificity, accuracy, precision, and F1-score of the elastic net were higher than those of the ANN. According to the purpose of the study, two models can be used simultaneously. Based on the results of models, morphology, tumor differentiation, and age had a greater effect on death. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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