Responders to first-line osteoarthritis treatment had reduced frequency of hip and knee joint replacements within 5 years: an observational register-based study of 44,311 patients.
Background and purpose -- First-line treatment (education, exercise) for patients with hip and knee osteoarthritis (OA) aims to reduce pain and improve function. We aimed to compare progression to joint replacement within 5 years between responders and non-responders to first-line treatment for hip...
| Publicado en: | Acta Orthopaedica Vol. 95; pp. 373 - 380 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Medical Journals Sweden AB
2024
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183125108&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183125108 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17453674 1BVL jtl: Acta Orthopaedica issn: 17453674 maglogo: N pubinfo: dt: 2024 vid: 95 pid: 59195 pub: Medical Journals Sweden AB artinfo: ui: 183125108 183125108 183125108 10.2340/17453674.2024.41011 183125108 ppf: 373 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Responders to first-line osteoarthritis treatment had reduced frequency of hip and knee joint replacements within 5 years: an observational register-based study of 44,311 patients. aug: au: GUSTAFSSON, Kristin CRONSTRÖM, Anna ROLFSON, Ola AGEBERG, Eva JÖNSSON, Therese affil: Unit of Physiotherapy, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping sug: subj: Osteoarthritis, Hip Therapy Osteoarthritis, Knee Therapy Therapeutic Exercise Patient Education Program Implementation Disease Progression Prevention and Control Treatment Outcomes Evaluation Time Factors Human Funding Source Sweden Male Female Middle Age Aged Nonexperimental Studies Prospective Studies Quality of Life Pain Management Signs and Symptoms Prevention and Control Comparative Studies Arthroplasty, Replacement, Knee Arthroplasty, Replacement, Hip Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background and purpose -- First-line treatment (education, exercise) for patients with hip and knee osteoarthritis (OA) aims to reduce pain and improve function. We aimed to compare progression to joint replacement within 5 years between responders and non-responders to first-line treatment for hip and knee OA, respectively. Methods -- This observational study included data for 30,524 knee OA and 13,787 hip OA patients from the Swedish Osteoarthritis Register, linked with the Swedish Arthroplasty Register, Statistics Sweden, and the Swedish Prescribed Drug Register. The primary prognostic factor was change in pain between baseline and 3-month followup, measured on a numeric rating scale (0-10, best to worst) where an improvement of = 2 was classified as responder and = 1 as non-responder. The main outcome was progression to joint replacement surgery within 5 years, assessed using baseline adjusted multivariable Cox regression analyses. Results -- At 5 years, in hip OA, 35% (95% confidence interval [CI] 32.2-37.2) of the responders and 48% (CI 45.9-49.5) of the non-responders and in knee OA 14% (CI 13.0-15.3) of the responders and 20% (CI 18.8-20.8) of the non-responders had progressed to joint replacement. Being a responder to the treatment was associated with having a lower probability of progression to surgery for both hip OA (hazard ratio [HR] 0.4, CI 0.4-0.5) and knee OA (HR 0.6, CI 0.5-0.6). Conclusion -- Patients with hip or knee OA who experienced pain relief after a first-line OA treatment program were less likely to progress to joint replacement surgery. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|