Reducing heart failure events via individualized patient education program in patients with reduced ejection fraction.
• Heart failure with reduced ejection fraction (HFrEF) significantly burdens individuals and healthcare systems by reducing life expectancy, increasing rehospitalization (RH), and lowering quality of life (QoL). • This pharmacist led IPEP for HFrEF patients reduces one-year rehospitalization and inc...
| Published in: | Heart & Lung Vol. 70; pp. 313 - 321 |
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| Main Authors: | , , , |
| Format: | research Journal Article |
| Published: |
Elsevier B.V.
Mar2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183209494&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183209494 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01479563 04L jtl: Heart & Lung issn: 01479563 maglogo: N pubinfo: dt: Mar2025 vid: 70 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 183209494 183209494 183209494 10.1016/j.hrtlng.2025.01.001 183209494 ppf: 313 ppct: 8 formats: tig: atl: Reducing heart failure events via individualized patient education program in patients with reduced ejection fraction. aug: au: Philip, Anu Shastry, Chakrakodi Shasidhara Utagi, Basavaraj Alex, Anjusha affil: Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore 575018, India sug: subj: Heart Failure Prevention and Control Patient Education Cardiac Patients Individualized Medicine Ventricular Ejection Fraction Pharmacists Program Evaluation Outcomes of Education Patient Compliance Quality of Life Human Male Female Prospective Studies Clinical Trials Descriptive Statistics Kaplan-Meier Estimator Survival Analysis Cox Proportional Hazards Model Chi Square Test Data Analysis Software Self Care Readmission Confidence Intervals Male Female ab: • Heart failure with reduced ejection fraction (HFrEF) significantly burdens individuals and healthcare systems by reducing life expectancy, increasing rehospitalization (RH), and lowering quality of life (QoL). • This pharmacist led IPEP for HFrEF patients reduces one-year rehospitalization and increases survival rates. • Participants in the IPEP demonstrate enhanced adherence to medication and disease-specific self-care practices, leading to improved QoL. • The combined effect of IPEP and guideline-directed medical therapy (GDMT), observed in the subgroup analysis of participants in the intervention group, can guide local, national, and international policies to improve the healthcare system for HFrEF patients. Disease management programs for heart failure (HF) often include various strategies such as medication management and lifestyle modifications, and are known to improve clinical outcomes. To evaluate the effectiveness of an individualized patient education program (IPEP) specifically designed for patients with reduced ejection fraction (HFrEF) on clinical outcomes. In our prospective interventional study involving 164 patients, participants were divided into control (CG) and intervention (IG) groups. The IG received the IPEP facilitated by the academic pharmacist, while both the IG and the CG continued to receive standard care from the healthcare team without any differences in the care provided. Self-care practices, medication adherence, quality of life, and clinical outcomes were assessed at both the 6th and 12th months. Statistical analysis included Chi-square tests, Kaplan-Meier survival plots, and Multivariable Cox proportional regression analysis. Data analysis was conducted using JAMOVI and R software. The demographic and clinical characteristics of sample population were largely homogeneous in both the groups. The unadjusted 1-year rehospitalization (RH) rate was significantly lower in the IG at 33 % compared to 48 % in the CG, with a hazard ratio of 0.55 (95 % CI: 0.34–0.90, p = 0.018). Kaplan-Meier survival analysis depicts a higher RH rate for HFrEF participants over time, with a significant difference observed between CG and IG (log-rank P = 0.017). Notable disparities in self-care practices emerged & at the 6th and 12th-month assessments medication adherence & QoL were significantly improved in the IG (p ≤ 0.001). IPEP led by an academic pharmacist resulted in improved self-care practices, enhanced quality of life, and reduced one-year rehospitalization rates. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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