Electroacupuncture therapy on non-motor symptoms of patients with Parkinson's disease: results of a pilot study.
Objective: This study aims to assess the effect of electroacupuncture (EA) on non-motor symptoms in Parkinson's disease (PD) patients as a primary goal and motor symptomatology as a secondary outcome. Methods: Twenty-five patients were enrolled in a non-controlled pilot study that involved a 10-sess...
| Publicado en: | Revista Mexicana de Neurociencia Vol. 26; no. 1; pp. 14 - 21 |
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| Autores principales: | , , , , , , |
| Formato: | Artículo |
| Publicado: |
Academia Mexicana de Neurologia
Jan/Feb2025
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Objective: This study aims to assess the effect of electroacupuncture (EA) on non-motor symptoms in Parkinson's disease (PD) patients as a primary goal and motor symptomatology as a secondary outcome. Methods: Twenty-five patients were enrolled in a non-controlled pilot study that involved a 10-session EA intervention in 16 acupoints, applied 3 times a week for 4 weeks. Motor, non-motor, cognitive, and quality of life evaluation were conducted before intervention and 7 days after concluding the last EA session through MDS-Unified PD rating scale (MDS-UPDRS), Non-motor Symptom Scale (NMSS), montreal cognitive assessment (MoCA), and PD questionnaire (PDQ-8), respectively. Results: Patients showed significantly lower scores in the MDS-UPDRS Part II (7.0 ± 5.7 vs. 10.5 ± 7.6, p = 0.046) and Part III (14.0 ± 8.6 vs. 23.1 ± 13.9, p = 0.002), and NMSS total score (35.2 ± 26.6 vs. 54.6 ± 32.5, p = 0.004) in the post-intervention evaluation, with mood/cognition domain of the NMSS being the only significantly affected by treatment. MoCA total score increased after the intervention (24.2 ± 4.5 vs. 21.6 ± 4.3, p = 0.020), while PDQ-8 scores were not significantly affected by the intervention. Conclusions: Non-motor and motor symptomatology were significantly improved after concluding a 10-session EA therapy. Mood and cognitive disorders were the most positively affected by the intervention. Evaluation of the long-term effects of EA in PD is further needed. Objetivos: Evaluar el efecto de la electroacupuntura (EA) sobre los síntomas no motores en pacientes con Enfermedad de Parkinson como objetivo principal y la sintomatología motora como resultado secundario. Métodos: Se incluyeron 25 pacientes en un estudio piloto no controlado cuya intervención implicó 10 sesiones de EA en 16 acupuntos, aplicada 3 veces por semana durante 4 semanas. Se realizó una evaluación motora, no motora, cognitiva y de calidad de vida antes de la intervención y siete días después de concluir la última sesión de EA mediante la escala unificada de la enfermedad de Parkinson modificada por la Sociedad de Trastornos del Movimiento (MDS-UPDRS), la escala de síntomas no motores (NMSS), Test Cognitivo de Montreal (MoCA) y cuestionario sobre la enfermedad de Parkinson 8 (PDQ-8), respectivamente. Resultados: En la evaluación posterior a la intervención, los pacientes mostraron scores significativamente menores en la Parte II (7.0 ± 5.7 vs. 10.5 ± 7.6, p = 0.046) y la Parte III (14.0 ± 8.6 vs. 23.1 ± 13.9, p = 0.002) de la MDS-UPDRS y en el score total del NMSS (35.2 ± 26.6 vs. 54.6 ± 32.5, p = 0.004), siendo el dominio del estado de ánimo/cognición del NMSS el único afectado significativamente. El score total del MoCA aumentó después de la intervención (24.2 ± 4.5 vs. 21.6 ± 4.3, p = 0.020), mientras que los scores del PDQ-8 no se vieron afectados significativamente. Conclusiones: La sintomatología motora y no motora mejoró significativamente después de concluir una terapia de EA de 10 sesiones. |
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