| Sumario: | Purpose: This study investigated the mediating effect of grit in the relationship between silence behavior and medication safety competence among nurses. Methods: The study included 166 nurses from four university hospitals and general hospitals in Seoul and Gyeonggi-do, South Korea. Data were collected from March 1 to 10, 2024, using self-report questionnaires. Data were analyzed using the t-test, analysis of variance, Scheffe's test, and Pearson's correlation coefficients with IBM SPSS Statistics ver. 23.0 (IBM Corp.). A mediation analysis was performed using Hayes's PROCESS macro model 4 and the bootstrapping method. Results: Medication safety competence showed significant correlations with silence behavior (r=--.21, p=.008) and grit (r=.43, p<.001). Furthermore, grit partially mediated the relationship between silence behavior and medication safety competence. Conclusion: This study indicates that grit is a significant mediator in the relationship between silence behavior and medication safety competence. Therefore, an integrated approach that reduces silence behavior and promotes grit is essential for strengthening nurses' medication safety competence. Ultimately, these strategies will help ensure patient safety by improving medication safety competence.
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