Multimodal Adaptations to Expiratory Musculature-Targeted Resistance Training: A Preliminary Study in Healthy Young Adults.
Purpose: Exercise-induced adaptations, including neuroplasticity, are well studied for physical exercise that targets skeletal muscles. However, little is known about the neuroplastic potential of targeted speech and swallowing exercises. The current study aimed to gather preliminary data on molecul...
| Publicado en: | Journal of Speech, Language & Hearing Research Vol. 68; no. 3; pp. 987 - 1006 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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American Speech-Language-Hearing Association
Mar2025
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=183476503&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 183476503 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Mar2025 vid: 68 iid: 3 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 183476503 10.1044/2024_JSLHR-24-00294 ppf: 987 ppct: 19 formats: fmt: @attributes: type: P size: 2.6MB tig: atl: Multimodal Adaptations to Expiratory Musculature-Targeted Resistance Training: A Preliminary Study in Healthy Young Adults. aug: au: Krishnamurthy, Rahul Schultz, Douglas H. Yingying Wang Natarajan, Sathish Kumar Barlow, Steven M. Dietsch, Angela M. affil: Department of Neurosurgery, University of Nebraska Medical Center, Omaha Department of Special Education and Communication Disorders, University of Nebraska--Lincoln Center for Brain, Biology, and Behavior, University of Nebraska--Lincoln Department of Psychology, University of Nebraska--Lincoln Department of Nutrition and Health Sciences, University of Nebraska--Lincoln Department of Biological Systems Engineering, University of Nebraska--Lincoln su: Statistical models Exercise physiology Physiological adaptation Phosphorylation Research funding Respiration Neuroplasticity Enzyme-linked immunosorbent assay Brain Descriptive statistics Magnetic resonance imaging Cellular signal transduction Resistance training Serum Brain-derived neurotrophic factor Protein-tyrosine kinases Somatomedin Respiratory muscles Respiratory mechanics Deglutition disorders Cell receptors Blood sug: subj: Diagnostic Imaging Centers Biological Product (except Diagnostic) Manufacturing Statistical models Exercise physiology Physiological adaptation Phosphorylation Research funding Respiration Neuroplasticity Enzyme-linked immunosorbent assay Brain Descriptive statistics Magnetic resonance imaging Cellular signal transduction Resistance training Serum Brain-derived neurotrophic factor Protein-tyrosine kinases Somatomedin Respiratory muscles Respiratory mechanics Deglutition disorders Cell receptors Blood ab: Purpose: Exercise-induced adaptations, including neuroplasticity, are well studied for physical exercise that targets skeletal muscles. However, little is known about the neuroplastic potential of targeted speech and swallowing exercises. The current study aimed to gather preliminary data on molecular and functional changes associated with the neuroplastic effects of 4-week expiratory musculature-targeted resistance training in healthy young adults. Method: Five healthy young adult men aged between 19 and 35 years, M (SD) = 28.8 (2.68) years, underwent 4 weeks of expiratory muscle strength training (EMST). We measured changes in maximum expiratory pressure (MEP), serum brain-derived neurotrophic factor (BDNF), and insulin-like growth factor 1 (IGF-1) levels at baseline and posttraining conditions. Furthermore, functional and structural magnetic resonance images were obtained to investigate the neuroplastic effects of EMST. We analyzed the effects of training using a linear mixed model for each outcome, with fixed effects for baseline and posttraining. Results: MEP and serum BDNF levels significantly increased posttraining. However, this effect was not observed for IGF-1. A significant increase in functional activation in eight regions was also observed posttraining. However, we did not observe significant changes in the white matter microstructure. Conclusions: Preliminary data from our study suggest targeted resistance training of expiratory muscles results in molecular and neuroplastic adaptations similar to exercise that targets skeletal muscles. Additionally, these results suggest that EMST could be a potential intervention to modulate (or prime) neurotrophic signaling pathways linked to functional strength gains and neuroplasticity. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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