New Constituents from Zanthoxylum rhoifolium.

The phytochemical study of Zanthoxylum rhoifolium apolar and medium polarity stem bark and leaf extracts afforded 29 compounds, including three new sesquiterpenes (1 – 3) and one new α -ionone glycoside (4). All compounds were characterized by means of 1D and 2D NMR and HRESIMS data. Furthermore, a...

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Published in:Planta Medica Vol. 91; no. 3; pp. 119 - 127
Main Authors: Stasi, Mauro Di, Parisi, Valentina, Hernandez, Vanessa, Gazzillo, Erica, Chini, Maria Giovanna, Bifulco, Giuseppe, Braca, Alessandra, Donadio, Giuliana, De Tommasi, Nunziatina
Format: equations & formulas pictorial research tables/charts Journal Article
Published: Georg Thieme Verlag Stuttgart 2025
Online Access:View this record in EBSCOhost
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      dt: 2025
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      pub: Georg Thieme Verlag Stuttgart
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        10.1055/a-2486-9139
        183502749
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        atl: New Constituents from Zanthoxylum rhoifolium.
      aug:
        au:
          Stasi, Mauro Di
          Parisi, Valentina
          Hernandez, Vanessa
          Gazzillo, Erica
          Chini, Maria Giovanna
          Bifulco, Giuseppe
          Braca, Alessandra
          Donadio, Giuliana
          De Tommasi, Nunziatina
        affil: Dipartimento di Farmacia, Università di Pisa, Pisa, Italy
      sug:
        subj:
          Plants, Medicinal Analysis
          Plant Extracts Analysis
          Plant Bark Analysis
          Antiinfective Agents Pharmacodynamics
          Gram-Positive Bacteria Drug Effects
          Gram-Negative Bacteria Drug Effects
          Molecular Structure
          Funding Source
          Hydrocarbons
          Hydrocarbons, Alicyclic
          Carotenoids
          Phytochemicals
          Microbial Culture and Sensitivity Tests
      ab: The phytochemical study of Zanthoxylum rhoifolium apolar and medium polarity stem bark and leaf extracts afforded 29 compounds, including three new sesquiterpenes (1 – 3) and one new α -ionone glycoside (4). All compounds were characterized by means of 1D and 2D NMR and HRESIMS data. Furthermore, a precise structural analysis was performed, employing a combined density functional theory (DFT)/NMR approach to elucidate the compounds configurations. The crude extracts were then tested against a panel of gram-positive and gram-negative bacteria by broth dilution methods to determine their minimal inhibitory concentration. In these experimental conditions, no interesting antimicrobial activity was observed.
      pubtype: Periodical
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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