Personality and cardiovascular mortality risk: a multi-cohort analysis in individuals with and without pre-existing cardiovascular disease.

This study investigated the associations between personality traits of the Five Factor Model and cardiovascular mortality, with a specific focus on whether pre-existing cardiovascular conditions modified these associations. We used data from 43,027 participants across five cohort studies: Health and...

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Published in:Journal of Behavioral Medicine Vol. 48; no. 1; pp. 111 - 120
Main Authors: Jokela, Markus, Pulkki-Råback, Laura, Elovainio, Marko, Batty, G. David, Kivimäki, Mika
Format: meta analysis research tables/charts Journal Article
Published: Springer Nature Feb2025
Online Access:View this record in EBSCOhost
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      dt: Feb2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10865-024-00528-9
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        atl: Personality and cardiovascular mortality risk: a multi-cohort analysis in individuals with and without pre-existing cardiovascular disease.
      aug:
        au:
          Jokela, Markus
          Pulkki-Råback, Laura
          Elovainio, Marko
          Batty, G. David
          Kivimäki, Mika
        affil: https://ror.org/040af2s02 Department of Psychology, University of Helsinki, Helsinki, Finland
      sug:
        subj:
          Personality
          Models, Psychological
          Cardiovascular Diseases Mortality
          Mortality Risk Factors
          Risk Assessment
          Human
          Descriptive Statistics
          Data Analysis Software
          Meta Analysis
          Confidence Intervals
          Odds Ratio
          Cox Proportional Hazards Model
      ab: This study investigated the associations between personality traits of the Five Factor Model and cardiovascular mortality, with a specific focus on whether pre-existing cardiovascular conditions modified these associations. We used data from 43,027 participants across five cohort studies: Health and Retirement Study (HRS); Wisconsin Longitudinal Study (WLS); National Social Life, Health, and Aging Project (NSHAP); Midlife in the United States (MIDUS); Household, Income, and Labour Dynamics in Australia (HILDA) with a mean age 55.9 years and 6493 individuals with pre-existing cardiovascular disease. We conducted meta-analyses examining conscientiousness, emotional stability, agreeableness, openness to experience, and extraversion in relation to mortality due to coronary heart disease and stroke. During a mean follow-up of 12.1 years, 1620 participants died from coronary heart disease and 454 from stroke. Lower conscientiousness was associated with higher mortality risk from both coronary heart disease (hazard ratio per 1SD = 0.82, 95%CI = 0.75–0.90) and stroke (HR = 0.84, CI = 0.72–0.99). Lower emotional stability predicted increased coronary heart disease mortality (HR = 0.91, CI = 0.85–0.97). The association between conscientiousness and cardiovascular mortality did not differ between individuals with or without baseline cardiovascular conditions. In addition, adjustments for health behaviors and other covariates only slightly attenuated this association. Other personality traits were not associated with cardiovascular disease mortality. Our findings highlight the role of low conscientiousness, and to a lesser extent low emotional stability, in the development and progression of fatal cardiovascular disease through pathways that may extend beyond established health behaviors.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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