Hypertensive Subjects are More Likely to Develop Coronary Artery Lesions: A Study by Computerised Tomography Coronary Angiography.

Coronary Computed Tomography Angiography (CCTA) is commonly used to identify coronary artery disease. In this study, the indications for CCTA referrals are reviewed, to identify the strongest predictors of CAD, as seen on CCTA. A retrospective study, reviewing the electronic health records of consec...

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Publicado en:Angiology Vol. 76; no. 2; pp. 166 - 174
Autores principales: Tserioti, Eleni, Chana, Harmeet, Salmasi, Abdul-Majeed
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. Feb2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2025
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        atl: Hypertensive Subjects are More Likely to Develop Coronary Artery Lesions: A Study by Computerised Tomography Coronary Angiography.
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          Tserioti, Eleni
          Chana, Harmeet
          Salmasi, Abdul-Majeed
        affil: 4957 Imperial College School of Medicine, London, UK
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        subj:
          Hypertension Complications
          Coronary Arteriosclerosis Risk Factors
          Coronary Arteriosclerosis Diagnosis
          Coronary Angiography Methods
          Computed Tomography Angiography Methods
          Referral and Consultation Evaluation
          Risk Assessment
          Human
          Male
          Female
          Middle Age
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          Retrospective Design
          Record Review
          Electronic Health Records
          Severity of Illness Indices
          Univariate Statistics
          Diabetes Mellitus
          Sex Factors
          Hyperlipidemia
          Smoking
          Chest Pain
          Multiple Logistic Regression
          Odds Ratio
          Statistical Significance
          Data Analysis Software
          Descriptive Statistics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
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      ab: Coronary Computed Tomography Angiography (CCTA) is commonly used to identify coronary artery disease. In this study, the indications for CCTA referrals are reviewed, to identify the strongest predictors of CAD, as seen on CCTA. A retrospective study, reviewing the electronic health records of consecutive patients who underwent CCTA between July and November 2020 at our Trust, was conducted. A total of 485 patient reports were reviewed. Of patients with moderate-to-severe CAD, 128 (73.6%) were hypertensive. Of those with severe CAD, 79 patients (76%) were hypertensive. Univariate analysis for comparison of patients with absent (n = 219), mild (n = 92), moderate (n = 70) and severe (n = 104) CAD revealed that hypertension (P <.001), diabetes mellitus (P <.001), gender (P <.001), dyslipidemia (P <.001) and smoking (P =.006), were each significantly associated with the presence of CAD on CCTA. However, multiple logistic regression analysis confirmed that hypertension has the strongest association with CAD (OR = 2.22, P <.001) Furthermore, the presence of typical chest pain in hypertensive patients was strongly associated with significant CAD, on CCTA. Among all risk factors, hypertension is the strongest independent predictor for the presence of CAD on CCTA. These results suggest that hypertension is a significant factor when considering referral for CCTA, particularly when associated with chest pain.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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