Substance use and psychiatric outcomes following substance use disorder treatment: An 18‐month prospective cohort study in Chile.
Background and aims: Evidence from high‐income countries has linked duration and compliance with treatment for substance use disorders (SUDs) with reductions in substance use and improvements in mental health. Generalizing these findings to other regions like South America, where opioid and injectio...
| Published in: | Addiction Vol. 120; no. 4; pp. 756 - 770 |
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| Main Authors: | , , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Apr2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183688534&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183688534 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Apr2025 vid: 120 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 183688534 183688534 183688534 10.1111/add.16731 183688534 ppf: 756 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Substance use and psychiatric outcomes following substance use disorder treatment: An 18‐month prospective cohort study in Chile. aug: au: Bórquez, Ignacio Krawczyk, Noa Matthay, Ellicott C. Charris, Rafael Dupré, Sofía Mateo, Mariel Carvacho, Pablo Cerdá, Magdalena Castillo‐Carniglia, Álvaro Valenzuela, Eduardo affil: Center for Opioid Epidemiology and Policy (COEP), Division of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York NY,, USA sug: subj: Substance Use Disorders Therapy Treatment Duration Patient Compliance Substance Use Disorders Prevention and Control Mental Disorders Prevention and Control Human Male Female Adult Middle Age Chile Prospective Studies Surveys Probability Outpatients Inpatients Psychiatric Patients Depression Prevention and Control Panic Disorder Prevention and Control Anxiety Prevention and Control Stress Disorders, Post-Traumatic Prevention and Control Alcoholic Beverages Cannabis Cocaine Descriptive Statistics Confidence Intervals Odds Ratio Funding Source Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background and aims: Evidence from high‐income countries has linked duration and compliance with treatment for substance use disorders (SUDs) with reductions in substance use and improvements in mental health. Generalizing these findings to other regions like South America, where opioid and injection drug use is uncommon, is not straightforward. We examined if length of time in treatment and compliance with treatment reduced subsequent substance use and presence of psychiatric comorbidities. Design: Prospective cohort analysis (3 assessments, 18 months) using inverse probability weighting to account for confounding and loss to follow‐up. Settings Outpatient/inpatient programs in Región Metropolitana, Chile. Participants: Individuals initiating publicly funded treatment (n = 399). Measurements Exposures included length of time in (0–3, 4–7, 8 + months, currently in) and compliance with treatment (not completed, completed, currently in) measured in the intermediate assessment (12 months). Primary outcomes were past‐month use of primary substance (most problematic) and current psychiatric comorbidities (major depressive episode, panic, anxiety or post‐traumatic stress disorders) measured 6 months later (18 months). Secondary outcomes included past month use of alcohol, cannabis, cocaine powder and cocaine paste. Findings 18.3% [95% confidence interval (CI) = 14.7%–22.6%] of individuals participated for 3 or fewer months in treatment and 50.1% (95% CI = 45.2%–55.1%) did not complete their treatment plan at 12 months. Participating for 8 + months in treatment was associated with lower risk of past month use of primary substance at 18 months [vs. 0–3 months, risk ratio (RR) = 0.62, 95% CI = 0.38–1.00] and completion of treatment (vs. not completed, RR = 0.49, 95% CI = 0.30–0.80). Neither participating 8 + months (vs. 0–3 months, RR = 0.83, 95% CI = 0.57–1.22) nor treatment completion (vs. not completed, RR = 1.02, 95% CI = 0.72–1.46) were associated with lower risk of psychiatric comorbidity at 18 months. Conclusions: Longer time in treatment and compliance with treatment for substance use disorders in Chile appears to be associated with lower risk of substance use but not current comorbid psychiatric conditions 18 months after treatment initiation. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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