Using a Functional Upper Limb Motor Task to Predict Cognitive and Functional Decline in Mild Cognitive Impairment and Alzheimer's Disease.
Background: Predicting the rate of cognitive and functional decline over the course of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) is vital for advancing clinical care and research initiatives. Objectives: The current study examined if a functional upper limb motor task could predic...
| Publicado en: | Neurorehabilitation & Neural Repair Vol. 39; no. 3; pp. 226 - 230 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Mar2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183813504&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183813504 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15459683 IRK jtl: Neurorehabilitation & Neural Repair issn: 15459683 maglogo: Y pubinfo: dt: Mar2025 vid: 39 iid: 3 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 183813504 182034743 183813504 183813504 10.1177/15459683241309591 183813504 ppf: 226 ppct: 4 formats: tig: atl: Using a Functional Upper Limb Motor Task to Predict Cognitive and Functional Decline in Mild Cognitive Impairment and Alzheimer's Disease. aug: au: Koppelmans, Vincent Duff, Kevin Schaefer, Sydney Y. affil: Department of Psychiatry, University of Utah, Salt Lake City, UT, USA sug: subj: Upper Extremity Physiology Motor Activity Task Performance and Analysis Geriatric Functional Assessment Disease Progression Risk Factors Risk Assessment Mild Cognitive Impairment Alzheimer's Disease Funding Source Human Comparative Studies Questionnaires Severity of Illness Indices Descriptive Statistics Aged Aged, 80 and Over Male Female Psychological Tests Neuropsychological Tests Clinical Assessment Tools Prediction Models Linear Regression Aged: 65+ years Aged, 80 & over Male Female ab: Background: Predicting the rate of cognitive and functional decline over the course of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) is vital for advancing clinical care and research initiatives. Objectives: The current study examined if a functional upper limb motor task could predict 1-year change in cognition (Mini Mental Status Examination [MMSE]) and daily function (Quick Dementia Rating System [QDRS]) from a sample of 61 cognitively intact, 35 MCI, and 32 AD subjects. Results: Analyses adjusted for age, sex, and education showed that performance speed and variability on the motor task significantly predicted change in performance on the MMSE and QDRS over 1 year, and that these effects were small to medium in size (η2 = 0.04-0.05). Conclusion: These results suggest the potential of a simple motor task to estimate disease progression in MCI and AD, which could be used to provide additional clinical resources for and enrich clinical trials with those most likely to decline. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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