The PREVASC study: Prospective REgistry of Valve disease in Asymptomatic Italian elderly SubjeCts.
Aims: Valvular heart disease (VHD) is the third leading cause of cardiovascular morbidity, with its incidence and public health impact projected to increase significantly. This study adopts a novel perspective, focusing on elderly individuals residing in rural areas, highlighting the unique dynamics...
| Publicado en: | Aging Clinical & Experimental Research Vol. 37; no. 1; pp. 1 - 11 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
3/20/2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183892244&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183892244 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15940667 2WMP jtl: Aging Clinical & Experimental Research issn: 15940667 maglogo: N pubinfo: dt: 3/20/2025 vid: 37 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 183892244 183892244 183892244 10.1007/s40520-025-02937-5 183892244 ppf: 1 ppct: 10 formats: tig: atl: The PREVASC study: Prospective REgistry of Valve disease in Asymptomatic Italian elderly SubjeCts. aug: au: Carrabba, Nazario Amico, Mattia Alexis Busi, Gherardo Vannini, Matteo Bruscoli, Filippo Fortunato, Salvatore Arcari, Luciano Di Lorenzo, Emilio Luzi, Giampaolo Clemenza, Francesco Amico, Francesco Pes, Giuseppe Merlo, Marco Sinagra, Gianfranco Desideri, Giovambattista Vetta, Francesco Mugelli, Alessandro Marchionni, Niccolo Boccanelli, Alessandro Vitillo, Paolo affil: https://ror.org/02crev113 Cardio-Thoracic-Vascular Department, A.O.U Careggi, Florence, Italy sug: subj: Registries, Disease Heart Valve Diseases Epidemiology Research, Medical Public Health Rural Areas Italy Heart Valve Diseases Symptoms Human Male Female Aged Multicenter Studies Nonexperimental Studies Italy Heart Valve Diseases Prognosis Incidence Prospective Studies Quality of Life In Old Age Questionnaires Echocardiography Severity of Illness Age Factors Mitral Valve Insufficiency Risk Factors Health Status Descriptive Statistics Cardiovascular Risk Factors Prevention and Control Aged: 65+ years Male Female ab: Aims: Valvular heart disease (VHD) is the third leading cause of cardiovascular morbidity, with its incidence and public health impact projected to increase significantly. This study adopts a novel perspective, focusing on elderly individuals residing in rural areas, highlighting the unique dynamics of small-town settings. Methods: This multicenter, observational study was conducted from May 2022 to September 2023, under the coordination of the AOU Careggi Echo Core-Lab, which managed the entire screening program. In 10 small Italian villages, each municipality facilitated the enrollment of asymptomatic individuals aged ≥ 65 years, with no prior VHD history, through voluntary participation. Participants were grouped into three age categories (65–69, 70–74, and ≥ 75 years) and underwent a thorough evaluation, including a Quality of Life (QoL) questionnaire and comprehensive echocardiographic assessment focusing on VHD detection and grading. Results: Among 1,113 participants, the prevalence and severity of VHD showed a significant increase with age (p < 0.0001). Remarkably, 94% of individuals aged ≥ 75 years had at least one valvular defect, with 22.5% presenting moderate or severe valvulopathy, including a prevalence of 4.8% for moderate or severe aortic valve stenosis and 7.5% for mitral regurgitation. Right-sided valvulopathies followed a similar trend, affecting 71.9% of elderly participants. QoL evaluations revealed a generally positive perceived health status, with a mean score of 77 ± 16. Conclusions: Our registry highlights that the prevalence of VHD in asymptomatic individuals over 65 years living in small Italian communities is substantial, increases with age, and is predominantly degenerative in etiology. Notably, most individuals with undiagnosed VHD perceived themselves as healthy. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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