The association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries.

Studies from high-income countries have shown that multimorbidity is associated with increased fall risk among older adults. However, studies specifically on this topic from low- and middle-income counties (LMICs) are lacking. Thus, we aimed to assess this association among adults aged ≥ 50 years fr...

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Publicado en:European Journal of Ageing Vol. 22; no. 1; pp. 1 - 11
Autores principales: Smith, Lee, López Sánchez, Guillermo F., Shin, Jae Il, Oh, Hans, Kostev, Karel, Tully, Mark A., Barnett, Yvonne, Butler, Laurie T., Veronese, Nicola, Soysal, Pinar, Jacob, Louis, Koyanagi, Ai
Formato: Artículo
Publicado: Springer Nature 3/20/2025
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 3/20/2025
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        10.1007/s10433-025-00848-y
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        atl: The association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries.
      aug:
        au:
          Smith, Lee
          López Sánchez, Guillermo F.
          Shin, Jae Il
          Oh, Hans
          Kostev, Karel
          Tully, Mark A.
          Barnett, Yvonne
          Butler, Laurie T.
          Veronese, Nicola
          Soysal, Pinar
          Jacob, Louis
          Koyanagi, Ai
        affil:
          https://ror.org/0009t4v78 Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK
          https://ror.org/03p3aeb86 Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain
          https://ror.org/01wjejq96 Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea
          https://ror.org/01wjejq96 Institute of Convergence Science, Severance Underwood Meta-Research Center, Yonsei University, Seoul, Republic of Korea
          https://ror.org/03taz7m60 Suzanne Dworak Peck School of Social Work, University of Southern California, Los Angeles, CA, USA
          University Clinic of Marburg, Marburg, Germany
          https://ror.org/01yp9g959 School of Medicine, Ulster University, Londonderry, Northern Ireland, UK
          https://ror.org/00qvkm315 Saint Camillus International University of Health Sciences, Faculty of Medicine, Rome, Italy
          https://ror.org/04z60tq39 Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey
          Research and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain
          https://ror.org/05f82e368 Assistance Publique - Hôpitaux de Paris (AP-HP) / Université Paris Cité, Lariboisière - Fernand Widal Hospital, Department of Physical Medicine and Rehabilitation, Paris, France
          Inserm / Université Paris Cité, UMR 1153, CRESS, Epidemiology of Ageing and Neurodegenerative Diseases (EpiAgeing), Paris, France
      su:
        Cross-sectional method
        Self-evaluation
        Health status indicators
        Chronic diseases
        Sleep
        Mental depression
        Cognition
        Middle age
        Old age
        Injury risk factors
        Risk assessment
        Middle-income countries
        Multiple regression analysis
        Descriptive statistics
        Odds ratio
        Factor analysis
        Confidence intervals
        Accidental falls
        Comorbidity
        Low-income countries
        Physical activity
        Grip strength
        Physical mobility
      sug:
        subj:
          Cross-sectional method
          Self-evaluation
          Health status indicators
          Chronic diseases
          Sleep
          Mental depression
          Cognition
          Middle age
          Old age
          Injury risk factors
          Risk assessment
          Middle-income countries
          Multiple regression analysis
          Descriptive statistics
          Odds ratio
          Factor analysis
          Confidence intervals
          Accidental falls
          Comorbidity
          Low-income countries
          Physical activity
          Grip strength
          Physical mobility
      keyword:
        Chronic disease
        Epidemiology
        Falls
        Low-and middle-income countries
        Medical and Health Sciences Public Health and Health Services
        Multimorbidity
        Chronic disease
        Epidemiology
        Falls
        Low-and middle-income countries
        Medical and Health Sciences Public Health and Health Services
        Multimorbidity
      ab: Studies from high-income countries have shown that multimorbidity is associated with increased fall risk among older adults. However, studies specifically on this topic from low- and middle-income counties (LMICs) are lacking. Thus, we aimed to assess this association among adults aged ≥ 50 years from six LMICs. Cross-sectional, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analyzed. Eleven chronic physical conditions were assessed. The presence of past 12-month fall-related injury was ascertained through self-reported information. Multivariable logistic regression and mediation analysis was conducted to assess the association between multimorbidity and fall-related injury. Data on 34,129 adults aged ≥ 50 years [mean (SD) age 62.4 (16.0) years; males 48.0%] were analyzed. Overall, compared to having no chronic conditions, having 2, 3, and ≥ 4 chronic conditions were significantly associated with 1.67 (95%CI = 1.21–2.30), 2.64 (95%CI = 1.89–3.68), and 3.67 (95%CI = 2.42–5.57) times higher odds for fall-related injury. The association between multimorbidity (i.e., ≥ 2 chronic conditions) and fall-related injury was mainly explained by pain/discomfort (mediated% 39.7%), mobility (34.1%), sleep/energy (24.2%), and cognition (13.0%). Older adults with multimorbidity in LMICs are at increased odds for fall-related injury. Targeting the identified potential mediators among those with multimorbidity may reduce fall risk in this population.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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