Lower Risk of New‐Onset Atrial Fibrillation in Conduction System Pacing Compared With Right Ventricular Pacing.
Background: Conduction system pacing (CSP) has been reported to improve clinical outcomes in comparison of right ventricular pacing (RVP). However, the performance between CSP and RVP on the risk of new‐onset atrial fibrillation (AF) remains elusive. Methods: Four online databases were systematicall...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 48; no. 2; pp. 202 - 216 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183898054&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183898054 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Feb2025 vid: 48 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 183898054 183898054 183898054 10.1111/pace.15121 183898054 ppf: 202 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Lower Risk of New‐Onset Atrial Fibrillation in Conduction System Pacing Compared With Right Ventricular Pacing. aug: au: Li, Feng Zhang, You Huang, Jian Peng, Si‐Liang Jin, Meng‐Chao Geng, Chi Ravi, Venkatesh Sharma, Parikshit S. Vijayaraman, Pugazhendhi Li, Hui affil: Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou Jiangsu,, China sug: subj: Cardiac Pacing, Artificial Methods Heart Conduction System Heart Ventricle, Right Physiology Atrial Fibrillation Prevention and Control Funding Source Human Systematic Review Descriptive Statistics Data Analysis Software PubMed Embase Cochrane Library Confidence Intervals Chi Square Test ab: Background: Conduction system pacing (CSP) has been reported to improve clinical outcomes in comparison of right ventricular pacing (RVP). However, the performance between CSP and RVP on the risk of new‐onset atrial fibrillation (AF) remains elusive. Methods: Four online databases were systematically searched up to July 1, 2024. Studies comprising the rate/risk of new‐onset AF between CSP and RVP group were included. Subgroup analysis was performed to screen the potential determinants for the new‐onset AF risk for CSP therapy. The pooled risk of new‐onset AF based on ventricular pacing burden (Vp) between CSP and RVP group were evaluated. Results: A total of six studies including 1577 patients requiring pacing therapy were eligible. The pooled new‐onset AF rates for CSP and RVP group were 0.09 and 0.27, respectively. Compared with RVP group, CSP group showed a lower pooled risk (risk ratio [RR] 0.38, p = 0.000) and adjusted risk (hazard ratio [HR] 0.32, p = 0.000) of new‐onset AF. Meanwhile, a significant intervention–covariate interaction for the adjusted risk of new‐onset AF between CSP and RVP group was identified with Vp < 20% and Vp ≥ 20%. Conclusions: Our study suggests that CSP is associate with a significantly lower occurrence of new‐onset AF compared with RVP. The Vp ≥ 20% may be the key determinant on the lower risk of new‐onset AF with CSP therapy. Trial Registration: https://www.crd.york.ac.uk/prospero/display%5frecord.php?ID=CRD42023492551, identifier (CRD42023492551) pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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