Pyoderma Gangrenosum Improved with Dapsone and Prednisone: A Case Report.
Pyoderma gangrenosum is a rare ulcerative condition that poses diagnostic and therapeutic challenges. Diagnosis and appropriate management are often delayed due to its rarity and the presence of numerous clinical variants. In this case report, the authors present the case of a 36-year-old man who ha...
| Published in: | Advances in Skin & Wound Care Vol. 38; no. 3; pp. 165 - 168 |
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| Main Authors: | , |
| Format: | case study pictorial Journal Article |
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Lippincott Williams & Wilkins
Apr2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=183911482&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 183911482 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15277941 38T jtl: Advances in Skin & Wound Care issn: 15277941 maglogo: N pubinfo: dt: Apr2025 vid: 38 iid: 3 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 183911482 183911482 183911482 10.1097/ASW.0000000000000250 183911482 ppf: 165 ppct: 3 formats: tig: atl: Pyoderma Gangrenosum Improved with Dapsone and Prednisone: A Case Report. aug: au: Merilleno, Arbie Sofia P. Ang-Tiu, Charlene Marie affil: Arbie Sofia P. Merilleno, MD, DPDS, is an Inflammatory Disease Fellow, University of Toronto, Ontario, Canada sug: subj: Pyoderma Gangrenosum Diagnosis Pyoderma Gangrenosum Drug Therapy Dapsone Administration and Dosage Dapsone Therapeutic Use Prednisone Administration and Dosage Prednisone Therapeutic Use Antiinfective Agents Therapeutic Use Drug Therapy, Combination Methods Rare Diseases Male Adult Skin Ulcer Etiology Dermatology Inflammation Complications Treatment Outcomes Resource-Limited Settings Adrenal Cortex Hormones Administration and Dosage Administration, Oral Adult: 19-44 years Male ab: Pyoderma gangrenosum is a rare ulcerative condition that poses diagnostic and therapeutic challenges. Diagnosis and appropriate management are often delayed due to its rarity and the presence of numerous clinical variants. In this case report, the authors present the case of a 36-year-old man who had long-standing and nonhealing ulcers that did not respond to multiple antibiotics and serial wound debridement. The patient was promptly initiated on oral corticosteroids and dapsone as an adjunctive steroid agent. After 6 months, the patient reported complete resolution of the lesions. This rare case underscores the potential value of combining prednisone and dapsone as a treatment option for pyoderma gangrenosum, particularly in resource-limited settings. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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