Optimizing metabolic health with digital twins.

A hallmark of subclinical metabolic decline is impaired metabolic flexibility, which refers to the ability to switch fuel utilization between glucose and fat according to energy demand and substrate availability. Herein, we propose optimizing metabolic health with digital twins that model an individ...

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Publicado en:NPJ Aging Vol. 11; no. 1; pp. 1 - 11
Autores principales: Su, Chengxun, Wang, Peter, Foo, Nigel, Ho, Dean
Formato: pictorial review tables/charts Journal Article
Publicado: Springer Nature 3/24/2025
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Optimizing metabolic health with digital twins.
      aug:
        au:
          Su, Chengxun
          Wang, Peter
          Foo, Nigel
          Ho, Dean
        affil: https://ror.org/01tgyzw49 The Institute for Digital Medicine (WisDM), National University of Singapore, Singapore, Singapore
      sug:
        subj:
          Metabolic Diseases Diagnosis
          Digital Health Economics
          Wearable Sensors Economics
          Metabolic Diseases Prevention and Control
          Early Diagnosis
          Cardiometabolic Risk Factors Prevention and Control
          Community Health Services
          Decision Making, Clinical
          Healthy Aging
          Socioeconomic Factors
          Public Health
          Health Promotion
      ab: A hallmark of subclinical metabolic decline is impaired metabolic flexibility, which refers to the ability to switch fuel utilization between glucose and fat according to energy demand and substrate availability. Herein, we propose optimizing metabolic health with digital twins that model an individual's metabolic flexibility profile to gamify the process of health optimization and predict long-term health outcomes. We explore key characteristics of this approach from technological and socioeconomical perspectives, with the objective of reducing the burden from metabolic disorders through driving behavior change and early detection of metabolic decline.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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