JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging.

Purpose: Prostate-specific membrane antigen (PSMA) radioligand therapy is a promising treatment for metastatic castration-resistant prostate cancer (mCRPC). Several beta or alpha particle-emitting radionuclide-conjugated small molecules have shown efficacy in late-stage mCRPC and one, [[177Lu]Lu]Lu-...

Descripción completa

Detalles Bibliográficos
Publicado en:European Journal of Nuclear Medicine & Molecular Imaging Vol. 52; no. 5; pp. 1631 - 1642
Autores principales: Nedelcovych, Michael T., Dash, Ranjeet P., Wu, Ying, Choi, Eun Yong, Lapidus, Rena S., Majer, Pavel, Jančařík, Andrej, Abou, Diane, Penet, Marie-France, Nikolopoulou, Anastasia, Amor-Coarasa, Alex, Babich, John, Thorek, Daniel L., Rais, Rana, Kratochwil, Clemens, Slusher, Barbara S.
Formato: Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost