Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS.

Background: Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship...

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Publicado en:Echocardiography Vol. 42; no. 3; pp. 1 - 12
Autores principales: Du, Bang, Liang, Shuxin, Zhang, Rui, Shi, Wenjia, Wang, Ruonan, Qin, Yahong, Chu, Aiai
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Mar2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS.
      aug:
        au:
          Du, Bang
          Liang, Shuxin
          Zhang, Rui
          Shi, Wenjia
          Wang, Ruonan
          Qin, Yahong
          Chu, Aiai
        affil: Department of Echocardiography, The First Clinical Medical School of Gansu University of Chinese Medicine, Gansu Provincial Hospital, Lanzhou, China
      sug:
        subj:
          Heart Atrium, Right Physiology
          Ventricular Function, Right Evaluation
          Exercise Tolerance
          Sleep Apnea, Obstructive
          Human
          Prospective Studies
          Echocardiography
          Exercise Test, Cardiopulmonary
          Tricuspid Valve Physiology
          Descriptive Statistics
          Funding Source
      ab: Background: Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship with exercise capacity. Methods: Fifty‐three patients with OSAS and thirty age‐ and gender‐matched controls prospectively underwent echocardiography and cardiopulmonary exercise testing to investigate RV diastolic function, RA function, and exercise capacity. Results: Altered RV diastolic function in patients with severe OSAS was indicated by the increased tricuspid valve E/e′ ratio (TV E/e′), isovolumic relaxation time (IVRT), and by the reduced RV TDI e′ velocity. The TV E/e′ correlated modestly with peak VO2 (r = −0.334, p < 0.01). Patients with severe OSAS exhibited impaired RA total emptying fraction, RA passive emptying fraction, and RA reservoir strain (RARS), with RARS being associated with peak oxygen uptake (VO2) (r = 0.451, p < 0.01 for reservoir function). Conclusion: Altered RA function and RV diastolic function in patients with OSAS are associated with impaired exercise capacity. The correlation of RA function and RV diastolic function with exercise capacity suggests that it may be important to evaluate RA function and RV diastolic function in this population.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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