Deep Learning-Based Model for Non-invasive Hemoglobin Estimation via Body Parts Images: A Retrospective Analysis and a Prospective Emergency Department Study.

Anemia is a significant global health issue, affecting over a billion people worldwide, according to the World Health Organization. Generally, the gold standard for diagnosing anemia relies on laboratory measurements of hemoglobin. To meet the need in clinical practice, physicians often rely on visu...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 2; pp. 775 - 793
Autores principales: Lin, En-Ting, Lu, Shao-Chi, Liu, An-Sheng, Ko, Chia-Hsin, Huang, Chien-Hua, Tsai, Chu-Lin, Fu, Li-Chen
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Deep Learning-Based Model for Non-invasive Hemoglobin Estimation via Body Parts Images: A Retrospective Analysis and a Prospective Emergency Department Study.
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          Lin, En-Ting
          Lu, Shao-Chi
          Liu, An-Sheng
          Ko, Chia-Hsin
          Huang, Chien-Hua
          Tsai, Chu-Lin
          Fu, Li-Chen
        affil: https://ror.org/05bqach95 Department of Computer Science and Information Engineering, National Taiwan University, CSIE Der Tian Hall No. 1, Sec. 4, Roosevelt Road, 106319, Taipei, Taiwan
      sug:
        subj:
          Anemia Diagnosis
          Anemia Blood
          Hemoglobins Blood
          Deep Learning
          Image Interpretation, Computer Assisted
          Emergency Service
          Prediction Models
          Human
          Male
          Female
          Retrospective Design
          Record Review
          Models, Statistical
          Data Analysis Software
          Descriptive Statistics
          Funding Source
          Male
          Female
      ab: Anemia is a significant global health issue, affecting over a billion people worldwide, according to the World Health Organization. Generally, the gold standard for diagnosing anemia relies on laboratory measurements of hemoglobin. To meet the need in clinical practice, physicians often rely on visual examination of specific areas, such as conjunctiva, to assess pallor. However, this method is subjective and relies on the physician's experience. Therefore, we proposed a deep learning prediction model based on three input images from different body parts, namely, conjunctiva, palm, and fingernail. By incorporating additional body part labels and employing a fusion attention mechanism, the model learns and enhances the salient features of each body part during training, enabling it to produce reliable results. Additionally, we employ a dual loss function that allows the regression model to benefit from well-established classification methods, thereby achieving stable handling of minority samples. We used a retrospective data set (EYES-DEFY-ANEMIA) to develop this model called Body-Part-Anemia Network (BPANet). The BPANet showed excellent performance in detecting anemia, with accuracy of 0.849 and an F1-score of 0.828. Our multi-body-part model has been validated on a prospectively collected data set of 101 patients in National Taiwan University Hospital. The prediction accuracy as well as F1-score can achieve as high as 0.716 and 0.788, respectively. To sum up, we have developed and validated a novel non-invasive hemoglobin prediction model based on image input from multiple body parts, with the potential of real-time use at home and in clinical settings.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
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      ougenre: Article
    language: English
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