Unsupervised and Self-supervised Learning in Low-Dose Computed Tomography Denoising: Insights from Training Strategies.

In recent years, X-ray low-dose computed tomography (LDCT) has garnered widespread attention due to its significant reduction in the risk of patient radiation exposure. However, LDCT images often contain a substantial amount of noises, adversely affecting diagnostic quality. To mitigate this, a plet...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 2; pp. 902 - 931
Autores principales: Zhao, Feixiang, Liu, Mingzhe, Xiang, Mingrong, Li, Dongfen, Jiang, Xin, Jin, Xiance, Lin, Cai, Wang, Ruili
Formato: algorithm diagnostic images equations & formulas pictorial review tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01213-8
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        atl: Unsupervised and Self-supervised Learning in Low-Dose Computed Tomography Denoising: Insights from Training Strategies.
      aug:
        au:
          Zhao, Feixiang
          Liu, Mingzhe
          Xiang, Mingrong
          Li, Dongfen
          Jiang, Xin
          Jin, Xiance
          Lin, Cai
          Wang, Ruili
        affil: https://ror.org/03dd7qj98 School of Data Science and Artificial Intelligence, Wenzhou University of Technology, Ouhai District, 325000, Wenzhou, Zhejiang, China
      sug:
        subj:
          Tomography, X-Ray Computed Methods
          Machine Learning Methods
          Deep Learning Methods
          Self Care
          Image Processing, Computer Assisted Methods
          Radiation Dosage
          Sensitivity and Specificity
          X-Rays
          Diagnosis, Computer Assisted
      ab: In recent years, X-ray low-dose computed tomography (LDCT) has garnered widespread attention due to its significant reduction in the risk of patient radiation exposure. However, LDCT images often contain a substantial amount of noises, adversely affecting diagnostic quality. To mitigate this, a plethora of LDCT denoising methods have been proposed. Among them, deep learning (DL) approaches have emerged as the most effective, due to their robust feature extraction capabilities. Yet, the prevalent use of supervised training paradigms is often impractical due to the challenges in acquiring low-dose and normal-dose CT pairs in clinical settings. Consequently, unsupervised and self-supervised deep learning methods have been introduced for LDCT denoising, showing considerable potential for clinical applications. These methods' efficacy hinges on training strategies. Notably, there appears to be no comprehensive reviews of these strategies. Our review aims to address this gap, offering insights and guidance for researchers and practitioners. Based on training strategies, we categorize the LDCT methods into six groups: (i) cycle consistency-based, (ii) score matching-based, (iii) statistical characteristics of noise-based, (iv) similarity-based, (v) LDCT synthesis model-based, and (vi) hybrid methods. For each category, we delve into the theoretical underpinnings, training strategies, strengths, and limitations. In addition, we also summarize the open source codes of the reviewed methods. Finally, the review concludes with a discussion on open issues and future research directions.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        equations & formulas
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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