Feature-Based vs. Deep-Learning Fusion Methods for the In Vivo Detection of Radiation Dermatitis Using Optical Coherence Tomography, a Feasibility Study.

Acute radiation dermatitis (ARD) is a common and distressing issue for cancer patients undergoing radiation therapy, leading to significant morbidity. Despite available treatments, ARD remains a distressing issue, necessitating further research to improve prevention and management strategies. Moreov...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 2; pp. 1137 - 1147
Autores principales: Photiou, Christos, Cloconi, Constantina, Strouthos, Iosif
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Feature-Based vs. Deep-Learning Fusion Methods for the In Vivo Detection of Radiation Dermatitis Using Optical Coherence Tomography, a Feasibility Study.
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          Photiou, Christos
          Cloconi, Constantina
          Strouthos, Iosif
        affil: https://ror.org/02qjrjx09 Department of Electrical and Computer Engineering, KIOS Research and Innovation Center of Excellence, University of Cyprus, Nicosia, Cyprus
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        subj:
          Radiodermatitis Diagnosis
          Radiodermatitis Physiopathology
          Tomography, Optical Coherence Methods
          Image Processing, Computer Assisted
          Machine Learning
          Sensitivity and Specificity Evaluation
          Human
          Deep Learning
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Algorithms
          Descriptive Statistics
          In Vivo Studies
          Pilot Studies
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
      ab: Acute radiation dermatitis (ARD) is a common and distressing issue for cancer patients undergoing radiation therapy, leading to significant morbidity. Despite available treatments, ARD remains a distressing issue, necessitating further research to improve prevention and management strategies. Moreover, the lack of biomarkers for early quantitative assessment of ARD impedes progress in this area. This study aims to investigate the detection of ARD using intensity-based and novel features of Optical Coherence Tomography (OCT) images, combined with machine learning. Imaging sessions were conducted twice weekly on twenty-two patients at six neck locations throughout their radiation treatment, with ARD severity graded by an expert oncologist. We compared a traditional feature-based machine learning technique with a deep learning late-fusion approach to classify normal skin vs. ARD using a dataset of 1487 images. The dataset analysis demonstrates that the deep learning approach outperformed traditional machine learning, achieving an accuracy of 88%. These findings offer a promising foundation for future research aimed at developing a quantitative assessment tool to enhance the management of ARD.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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