Impact of Collagen Membrane in Vertical Ridge Augmentation Using Ti‐Reinforced PTFE Mesh: A Randomised Controlled Trial.

Aims: This non‐inferiority randomised clinical trial aimed to compare vertical bone gain (VBG), volumetric bone changes and incidence of complications after vertical ridge augmentation (VRA) using perforated titanium‐reinforced dense‐polytetrafluoroethylene (PTFE) mesh covered by a collagen membrane...

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Publicado en:Journal of Clinical Periodontology Vol. 52; no. 4; pp. 575 - 589
Autores principales: Urban, Istvan A., Serroni, Matteo, Dias, Debora R., Baráth, Zoltán, Forster, Andras, Araújo, Tiago G., Saleh, Muhammad H. A., Cucchi, Alessandro, Ravidà, Andrea
Formato: diagnostic images pictorial research tables/charts randomized controlled trial Journal Article
Publicado: Wiley-Blackwell Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
      vid: 52
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jcpe.14129
        184107023
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        atl: Impact of Collagen Membrane in Vertical Ridge Augmentation Using Ti‐Reinforced PTFE Mesh: A Randomised Controlled Trial.
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        au:
          Urban, Istvan A.
          Serroni, Matteo
          Dias, Debora R.
          Baráth, Zoltán
          Forster, Andras
          Araújo, Tiago G.
          Saleh, Muhammad H. A.
          Cucchi, Alessandro
          Ravidà, Andrea
        affil: Graduate Implant Dentistry, Loma Linda University, Loma Linda California,, USA
      sug:
        subj:
          Tooth Abnormalities Surgery
          Alveolar Process Surgery
          Dentistry, Operative Methods
          Collagen
          Titanium
          Polytetrafluoroethylene
          Treatment Outcomes
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Randomized Controlled Trials
          Random Assignment
          Comparative Studies
          Descriptive Statistics
          Bone Density
          Bone Regeneration
          Surgical Patients
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Aims: This non‐inferiority randomised clinical trial aimed to compare vertical bone gain (VBG), volumetric bone changes and incidence of complications after vertical ridge augmentation (VRA) using perforated titanium‐reinforced dense‐polytetrafluoroethylene (PTFE) mesh covered by a collagen membrane (CM) or used alone. Materials and Methods: Thirty patients with vertical bone defects were randomly assigned to receive VRA with either PTFE + CM or PTFE alone. Meshes were removed after 9 months. Clinical assessments included complication rates, pseudo‐periosteum type and bone density. VBG, effective regeneration rate and the need for additional augmentation were evaluated using CBCT reconstructions. Results: Non‐inferiority of PTFE alone compared with PTFE + CM was not demonstrated for absolute and relative VBG (4.5 ± 2.1 mm vs. 4.1 ± 2.7 mm, 79.2% ± 16.6% vs. 85.8% ± 10.6%, respectively), effective regeneration rates (69.3% ± 17.9% vs. 72.3% ± 16.4%, respectively) or complication rates (6.7% in both groups). A higher incidence of type 1 pseudo‐periosteum was observed in the PTFE + CM group. Conclusion: The non‐inferiority of PTFE alone compared with PTFE + CM for absolute VBG was not established. However, both techniques led to comparable outcomes for VBG, complication rates and bone density. The higher incidence of type 1 pseudo‐periosteum and lacking bone volume in the PTFE + CM group suggests that adding a collagen membrane may help prevent soft tissue ingrowth. Trial Registration:Clinicaltrials.gov identification number: NCT04843488
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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