Effects of Moringa oleifera leaves on the blood glucose, blood pressure, and lipid profile of type 2 diabetic subjects: A parallel group randomized clinical trial of efficacy.
Background: There is a paucity of information on the antidiabetic potential of graded amounts of Moringa leaves on diabetes human subjects. Aim: To ascertain the effeccts of Moringa leaves on type 2 diabetic subjects' blood glucose, blood pressure, and lipid profile levels in a rural Nigerian commun...
| Publicado en: | Nutrition & Health Vol. 31; no. 1; pp. 281 - 292 |
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| Autores principales: | , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Sage Publications Inc.
Mar2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184137375&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184137375 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02601060 NTH jtl: Nutrition & Health issn: 02601060 maglogo: Y pubinfo: dt: Mar2025 vid: 31 iid: 1 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 184137375 163897681 184137375 184137375 10.1177/02601060231176873 184137375 ppf: 281 ppct: 11 formats: tig: atl: Effects of Moringa oleifera leaves on the blood glucose, blood pressure, and lipid profile of type 2 diabetic subjects: A parallel group randomized clinical trial of efficacy. aug: au: C. Afiaenyi, Ifeoma K. Ngwu, Elizabeth M. Okafor, Adaobi Ayogu, Rufina NB affil: Department of Nutrition and Dietetics, 107769 University of Nigeria, Nsukka, Enugu, Nigeria sug: subj: Diabetes Mellitus, Type 2 Drug Therapy Plant Leaves Pharmacodynamics Blood Glucose Drug Effects Blood Pressure Drug Effects Lipids Drug Effects Rural Areas Nigeria Drug Efficacy Evaluation Human Nigeria Adult Randomized Controlled Trials Random Assignment Control Group Pretest-Posttest Control Group Design Plant Leaves Administration and Dosage Diabetic Patients Systolic Pressure Drug Effects Triglycerides Drug Effects Comparative Studies Paired T-Tests Analysis of Covariance Data Analysis Software Descriptive Statistics Adult: 19-44 years ab: Background: There is a paucity of information on the antidiabetic potential of graded amounts of Moringa leaves on diabetes human subjects. Aim: To ascertain the effeccts of Moringa leaves on type 2 diabetic subjects' blood glucose, blood pressure, and lipid profile levels in a rural Nigerian community. Methods: This study adopted a parallel group randomized control design. Participants included 40 adult male and female diabetic subjects who met the inclusion criteria and consented to participate in the study. The participants were randomly assigned to four groups. The control group was fed diets without Moringa oleifera leaves while the experimental groups received 20, 40, and 60 g of Moringa leaves respectively daily for 14 days in addition to the diets. The subjects' baseline data and post-intervention data were collected before and after the intervention, respectively. Data were analyzed using paired-sample t -test and analysis of covariance. Significance was accepted at p < 0.05. Results: The mean fasting blood glucose levels in all the groups did not differ significantly from one another. Group 3 had significantly (p = 0.01) lower mean systolic pressure (from 136.40 ± 7.66 to 123.90 ± 13.82) after the intervention. Group 3 subjects had a significant (p = 0.04) increase in their triglyceride values (from 123.80 ± 53.69 before intervention to 151.20 ± 41.47) after intervention. After adjusting for the pre-intervention values, there was no significant (p > 0.05) difference in all the parameters at the end of the intervention. Conclusion: There were marginal improvements in the parameters assessed which were not dose-dependent. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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