Three-dimensional semiquantitative evaluation of reactive emphysema in magnesium implant models.
Background: Magnesium alloys have great potentials as bioabsorbable implants, whereas the difficulty in evaluating hydrogen gas produced in the degradation process has hindered their research and development. In this study, we investigated the possibility of industrial microfocus X-ray computed tomo...
| Publicado en: | Minimally Invasive Therapy & Allied Technologies Vol. 34; no. 2; pp. 136 - 144 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Apr2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184162948&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184162948 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13645706 J4S jtl: Minimally Invasive Therapy & Allied Technologies issn: 13645706 maglogo: Y pubinfo: dt: Apr2025 vid: 34 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 184162948 180670131 184162948 184162948 10.1080/13645706.2024.2423250 184162948 ppf: 136 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Three-dimensional semiquantitative evaluation of reactive emphysema in magnesium implant models. aug: au: Hayashi, Yoshinori Odagiri, Kazuki Ishii, Yuji Yamamoto, Keiichi Takahashi, Tsuyoshi Yamashita, Kotaro Saito, Takuro Tanaka, Koji Yamamoto, Kazuyoshi Makino, Tomoki Kurokawa, Yukinori Eguchi, Hidetoshi Doki, Yuichiro Nakajima, Kiyokazu affil: Department of Next Generation Endoscopic Intervention (Project ENGINE), Graduate School of Medicine, Osaka University, Osaka, Japan sug: subj: Subcutaneous Emphysema Radiography Tomography, X-Ray Computed Magnesium Adverse Effects Prostheses and Implants Models, Biological Animal Studies Rabbits Data Analysis Software Staining and Labeling ab: Background: Magnesium alloys have great potentials as bioabsorbable implants, whereas the difficulty in evaluating hydrogen gas produced in the degradation process has hindered their research and development. In this study, we investigated the possibility of industrial microfocus X-ray computed tomography (micro-CT) for the precise evaluation of subcutaneous emphysematous changes in a rabbit implantation model. Methods: Magnesium plates with/without porous venting were implanted under skin defects on the backs of rabbits. The graft sites were examined by industrial micro-CT after sacrificing. The captured images were reconstructed three-dimensionally for volumetric analyses. The tissues of the graft site were also examined in the traditional histological investigation. Results: We were able to image and numerate the shape and volume of subcutaneous emphysema using industrial micro-CT. The volume of emphysema was suppressed by pores punched in samples, and this trend increased as the number of pores increased. In the traditional histological examination, inflammatory changes were observed, but the emphysema could not be measured quantitatively. Conclusions: Industrial micro-CT imaging makes it possible to visualize and evaluate magnesium-induced subcutaneous emphysema in animal experiment. This cross-border technology has the potential to be widely applied to other life science fields. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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