When Should Surgical Human Subject Research Involve Patients Who Are Incarcerated?

Surgical research involving patients who are incarcerated is fraught with ethical, logistical, and practical questions. This article first considers important moments in the history of research with people who are incarcerated and suggests how they have contributed to evolution in human subject rese...

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Publicado en:AMA Journal of Ethics Vol. 27; no. 4; pp. 283 - 291
Autores principales: Khan, Lubna, Hoffman, Marcus
Formato: CEU questions and answers tables/charts Journal Article
Publicado: American Medical Association Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
      vid: 27
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      pub: American Medical Association
      place: Chicago, Illinois
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        10.1001/amajethics.2025.283
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        atl: When Should Surgical Human Subject Research Involve Patients Who Are Incarcerated?
      aug:
        au:
          Khan, Lubna
          Hoffman, Marcus
        affil: General surgery resident in the Global Surgery Track at Baylor College of Medicine in Houston, Texas
      sug:
        subj:
          Surgery, Operative
          Research, Medical Ethical Issues
          Prisoners
          Research Subjects Ethical Issues
          Incarceration
          Education, Continuing (Credit)
          Clinical Trials
          Rules and Regulations
          Research, Medical
          Ethics
          Patient Participation
      ab: Surgical research involving patients who are incarcerated is fraught with ethical, logistical, and practical questions. This article first considers important moments in the history of research with people who are incarcerated and suggests how they have contributed to evolution in human subject research ethics and regulation. This article also examines the problem of limited data about surgical disease burden and describes barriers to enrolling individuals who are incarcerated in surgical clinical trials, including study exclusion criteria and clinician-investigator bias. Finally, this article recommends strategies for balancing human research subject protections with the need for equitable enrollment in surgical clinical trials, especially later-phase trials in which benefit is more likely than in early-phase trials.
      pubtype: Academic Journal
      doctype:
        CEU
        questions and answers
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      ougenre: Article
    language: English
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