Generative Artificial Intelligence in Anatomic Pathology.

Context.--Generative artificial intelligence (AI) has emerged as a transformative force in various fields, including anatomic pathology, where it offers the potential to significantly enhance diagnostic accuracy, workflow efficiency, and research capabilities. Objective.--To explore the applications...

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Publicado en:Archives of Pathology & Laboratory Medicine Vol. 149; no. 4; pp. 298 - 319
Autores principales: Brodsky, Victor, Ullah, Ehsan, Bychkov, Andrey, Song, Andrew H., Walk, Eric E., Louis, Peter, Rasool, Ghulam, Singh, Rajendra S., Mahmood, Faisal, Bui, Marilyn M., Parwani, Anil V.
Formato: pictorial review tables/charts Journal Article
Publicado: College of American Pathologists Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
      vid: 149
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      pub: College of American Pathologists
      place: Northfield, Illinois
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        10.5858/arpa.2024-0215-RA
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          Brodsky, Victor
          Ullah, Ehsan
          Bychkov, Andrey
          Song, Andrew H.
          Walk, Eric E.
          Louis, Peter
          Rasool, Ghulam
          Singh, Rajendra S.
          Mahmood, Faisal
          Bui, Marilyn M.
          Parwani, Anil V.
        affil: Department of Pathology and Immunology, Washington University School of Medicine in St Louis, St Louis, Missouri
      sug:
        subj:
          Artificial Intelligence, Generative
          Pathology, Clinical Methods
          Anatomy
          Workflow
          Diagnostic Errors Prevention and Control
          Education Standards
          Research Standards
          Automation
          Quality Control (Technology)
          Machine Learning
          Collaboration
          Ethics
      ab: Context.--Generative artificial intelligence (AI) has emerged as a transformative force in various fields, including anatomic pathology, where it offers the potential to significantly enhance diagnostic accuracy, workflow efficiency, and research capabilities. Objective.--To explore the applications, benefits, and challenges of generative AI in anatomic pathology, with a focus on its impact on diagnostic processes, workflow efficiency, education, and research. Data Sources.--A comprehensive review of current literature and recent advancements in the application of generative AI within anatomic pathology, categorized into unimodal and multimodal applications, and evaluated for clinical utility, ethical considerations, and future potential. Conclusions.--Generative AI demonstrates significant promise in various domains of anatomic pathology, including diagnostic accuracy enhanced through AI-driven image analysis, virtual staining, and synthetic data generation; workflow efficiency, with potential for improvement by automating routine tasks, quality control, and reflex testing; education and research, facilitated by AI-generated educational content, synthetic histology images, and advanced data analysis methods; and clinical integration, with preliminary surveys indicating cautious optimism for nondiagnostic AI tasks and growing engagement in academic settings. Ethical and practical challenges require rigorous validation, prompt engineering, federated learning, and synthetic data generation to help ensure trustworthy, reliable, and unbiased AI applications. Generative AI can potentially revolutionize anatomic pathology, enhancing diagnostic accuracy, improving workflow efficiency, and advancing education and research. Successful integration into clinical practice will require continued interdisciplinary collaboration, careful validation, and adherence to ethical standards to ensure the benefits of AI are realized while maintaining the highest standards of patient care.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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