Periodontal stability and treatment needs in patients antiresorptive therapy during supportive periodontal care: a retrospective case-control study.
Objectives: This study aimed to investigate periodontal stability and treatment needs in patients under antiresorptive therapy (ART) during supportive periodontal care (SPC), with a focus on medication-related osteonecrosis of the jaw (MRONJ) risk and reasons for tooth loss. Method and materials: In...
| Publicado en: | Quintessence International Vol. 56; no. 2; pp. 108 - 119 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Quintessence Publishing Company Inc.
Feb2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184317203&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184317203 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00336572 ILW jtl: Quintessence International issn: 00336572 maglogo: N pubinfo: dt: Feb2025 vid: 56 iid: 2 pid: 1935 pub: Quintessence Publishing Company Inc. place: Batavia, Illinois artinfo: ui: 184317203 184317203 184317203 10.3290/j.qi.b5876508 184317203 ppf: 108 ppct: 11 formats: tig: atl: Periodontal stability and treatment needs in patients antiresorptive therapy during supportive periodontal care: a retrospective case-control study. aug: au: Ciardo, Antonio Simon, Marlinde M. Rosse, Hanna-Sophie Awounvo, Sinclair Ti-Sun Kim affil: Senior Physician, Heidelberg University, Heidelberg Medical Faculty, Heidelberg University Hospital, Clinic for Oral, Dental and Maxillofacial Diseases, Clinic of Conservative Dentistry, Section of Periodontology, Heidelberg, Germany sug: subj: Periodontal Diseases Osteonecrosis Chemically Induced Tooth Loss Risk Factors Osteonecrosis Risk Factors Diphosphonates Adverse Effects Jaw Pathology Risk Assessment Health Services Needs and Demand Dental Care Treatment Outcomes Human Female Male Retrospective Design Case Control Studies Hemorrhage Osteoporosis Preventive Dentistry Periodontal Pocket Age Factors Diabetes Mellitus Smoking Regression T-Tests Data Analysis Software Descriptive Statistics Female Male ab: Objectives: This study aimed to investigate periodontal stability and treatment needs in patients under antiresorptive therapy (ART) during supportive periodontal care (SPC), with a focus on medication-related osteonecrosis of the jaw (MRONJ) risk and reasons for tooth loss. Method and materials: In this retrospective case-control study, records of 100 stage III/IV SPC patients (50 ART-exposed, 50 unexposed) were analyzed for probing pocket depth, clinical attachment level, bleeding on probing, history of periodontal surgery, tooth loss, and MRONJ risk over a period of up to 15years after active periodontal therapy. Results: Baseline patient characteristics were similar between ART-exposed and unexposed patients. Osteoporosis was the underlying condition for ART in 72% of cases, and 74% exhibited an intermediate MRONJ risk profile. Over time, no significant differences between the groups were found in number of teeth, clinical attachment level, probing pocket depth, or bleeding on probing. Periodontal retreatment needs (teeth with probing pocket depth>4mm or>6mm) were relatively low and comparable between exposed and unexposed patients. However, periodontal surgery was performed more frequently in unexposed patients, also due to the risk of MRONJ in exposed patients. Both groups showed similar numbers of tooth loss, primarily due to periodontal and endodontic causes. Regression analyses identified ART, age, and diabetes mellitus as significant factors associated with higher bleeding on probing, while smoking and diabetes mellitus were linked to higher probing pocket depths. Conclusion: Achieving periodontal stability during SPC in ART-patients, most of whom had an intermediate MRONJ risk profile, appeared comparable to unexposed patients. However, the different MRONJ risk profiles should be taken into consideration and further investigated. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|