Willingness to Use Oral and Long-Acting Injectable PrEP in Substance-Using Men who have Sex with Men (SU-MSM) in High HIV Incidence Southern U.S. Cities: A NIDA Clinical Trials Network Study.

In Southern U.S. states with high HIV incidence and low HIV Pre-Exposure Prophylaxis (PrEP) uptake, enhanced efforts to increase interest in and willingness to use PrEP are needed. This implementation survey examined the associations of sociodemographic background, substance use, and sexual risk beh...

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Publicado en:AIDS & Behavior Vol. 29; no. 4; pp. 1192 - 1205
Autores principales: Tross, Susan, Laschober, Tanja C., Paschen-Wolff, Margaret, Ertl, Melissa, Nelson, C. Mindy, Wright, Lynette, Lancaster, Chloe, Feaster, Daniel J., Monger, Mauda, Toal, Phil, Fegley, Joshua P., Meche, David, Hankey, Colby, Woodhouse, Christina, Spector, Anya, Dresser, Lauren, Moran, Landhing, Jelstrom, Eve, Haynes, Louise, Shoptaw, Steven
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Willingness to Use Oral and Long-Acting Injectable PrEP in Substance-Using Men who have Sex with Men (SU-MSM) in High HIV Incidence Southern U.S. Cities: A NIDA Clinical Trials Network Study.
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          Tross, Susan
          Laschober, Tanja C.
          Paschen-Wolff, Margaret
          Ertl, Melissa
          Nelson, C. Mindy
          Wright, Lynette
          Lancaster, Chloe
          Feaster, Daniel J.
          Monger, Mauda
          Toal, Phil
          Fegley, Joshua P.
          Meche, David
          Hankey, Colby
          Woodhouse, Christina
          Spector, Anya
          Dresser, Lauren
          Moran, Landhing
          Jelstrom, Eve
          Haynes, Louise
          Shoptaw, Steven
        affil: https://ror.org/01esghr10 Columbia University Irving Medical Center, New York, NY, USA
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        subj:
          HIV Infections Epidemiology
          HIV Infections Prevention and Control
          Injections, Intramuscular
          Pre-Exposure Prophylaxis Utilization
          Administration, Oral
          Men Who Have Sex With Men United States
          Substance Abuse, Intravenous
          Human
          Funding Source
          Male
          Female
          Young Adult
          Adult
          United States
          Questionnaires
          HIV-Positive Persons
          HIV Infections Risk Factors
          Anti-HIV Agents Therapeutic Use
          Homosexuality
          Incidence
          Patient Attitudes
          Risk Taking Behavior
          Sexual Behavior
          Substance Use Disorders
          Analgesics, Opioid
          Sexual and Gender Minorities
          Descriptive Statistics
          Adult: 19-44 years
          Male
          Female
      ab: In Southern U.S. states with high HIV incidence and low HIV Pre-Exposure Prophylaxis (PrEP) uptake, enhanced efforts to increase interest in and willingness to use PrEP are needed. This implementation survey examined the associations of sociodemographic background, substance use, and sexual risk behaviors with willingness to use daily oral and long-acting injectable (LAI) PrEP among substance using men who have sex with men (SU-MSM). Participants were 225 SU-MSM recruited from sexually transmitted infection (STI) clinics, syringe services programs (SSPs), and substance use treatment programs (SUTPs) in eight Southern U.S. cities. Rates of willingness were high for both daily oral PrEP (78%) and LAI PrEP (66%). In multivariable analyses, distinct factors were associated with willingness towards each. For daily oral PrEP, greater willingness was associated with condomless anal sex, less frequent non-injection opioid use, prior PrEP awareness, and past use of PrEP. For LAI PrEP, greater willingness was associated with Black race, identifying as gay, being single, and higher injection drug use frequency. Lower willingness to use LAI PrEP was associated with higher non-injection opioid use frequency. Findings about willingness to use LAI PrEP, as a relatively newer modality, and greater willingness among Black SU-MSM as a disproportionately HIV-impacted population, are especially important. These findings argue for the necessity to enhance PrEP promotion efforts that distinguish between oral and LAI PrEP and that are specifically tailored to major SU-MSM subgroups in the Southern U.S.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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