Quantification of paravertebral cross-sectional muscle areas and fatty degeneration via magnetic resonance imaging in ankylosing spondylitis: a comprehensive analysis.

Aims: Ankylosing spondylitis (AS) is a chronic disease characterized by inflammation of the spine and joints. This study aimed to examine the multifidus (MF) and erector spinae (ES) muscles in AS patients using magnetic resonance imaging (MRI), and to evaluate the clinical implications of muscle fin...

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Publicado en:ARP Rheumatology Vol. 4; no. 1; pp. 13 - 20
Autores principales: Akkaya S., Sağlam Akkaya G., Demirulus S., Baykal Şahin H., Kılıç G., Çapkın E., Karkucak M.
Formato: Artículo
Publicado: Sociedade Portuguesa de Reumatologia Jan-Mar2025
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan-Mar2025
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      pub: Sociedade Portuguesa de Reumatologia
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        atl: Quantification of paravertebral cross-sectional muscle areas and fatty degeneration via magnetic resonance imaging in ankylosing spondylitis: a comprehensive analysis.
      aug:
        au:
          Akkaya S.
          Sağlam Akkaya G.
          Demirulus S.
          Baykal Şahin H.
          Kılıç G.
          Çapkın E.
          Karkucak M.
        affil:
          Department of Radiology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
          Department of Physical Medicine and Rehabilitation, Karadeniz Technical University, Trabzon, Turkey
      su:
        Mann Whitney U Test
        Ankylosing spondylitis
        Spondylitis
        Magnetic resonance imaging
        Erector spinae muscles
      sug:
        subj:
          Mann Whitney U Test
          Ankylosing spondylitis
          Spondylitis
          Magnetic resonance imaging
          Erector spinae muscles
      keyword:
        Chronic pain syndromes
        Muscle
        Spinal disorders
        Spondyloarthropathies
      ab: Aims: Ankylosing spondylitis (AS) is a chronic disease characterized by inflammation of the spine and joints. This study aimed to examine the multifidus (MF) and erector spinae (ES) muscles in AS patients using magnetic resonance imaging (MRI), and to evaluate the clinical implications of muscle findings. Methods: This study included 43 patients and 40 matched controls. The total (TCSA), functional (FCSA), relative CSAs, and ratios of MF and ES muscles were compared between the groups. The Visual Analog Scale, Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Disease Activity Score with CRP, Ankylosing Spondylitis Disease Activity Score with ESR, Bath Ankylosing Spondylitis Activity Index, and Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL) scores of AS patients were recorded. Comparisons between the two groups were made using the Student's t-test and the Mann-Whitney U test. Results: The TCSAs of the MF and ES were similar in the two groups. In contrast, MF relative FCSA (p = 0.003), ES relative FCSA (p < 0.001), ES FCSA (p = 0.017), MF FCSA/TCSA (p < 0.001), and ES FCSA/TCSA (p < 0.001) were decreased in AS patients. ES FCSA/TCSA was negatively correlated with BASMI (r = - 0.369, p = 0.015), while MF FCSA/TCSA was negatively correlated with BASMI, BASFI, and ASQoL (r = - 0.395, p = 0.009; r = - 0.321 p = 0.036; r = - 0.387, p = 0.010, respectively). Conclusions: The paravertebral muscle morphology significantly deteriorates in AS patients, exhibiting decreased functional muscle areas and increased fatty degeneration.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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      holder: Sociedade Portuguesa de Reumatologia
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          year: 2025
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