Estimating treatment effects from a randomized controlled trial with mid-trial design changes.
Background: In randomized controlled trials (RCTs), unplanned design modifications due to unexpected circumstances are seldom reported. Naively lumping data from pre- and post-design changes to estimate the size of the treatment effect, as planned in the original study, can introduce systematic bias...
| Publicado en: | Clinical Trials Vol. 22; no. 2; pp. 209 - 220 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications, Ltd.
Apr2025
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| Acceso en línea: | Ver este registro en EBSCOhost |