Adrenal Volume Quantitative Visualization Tool by Multiple Parameters and an nnU-Net Deep Learning Automatic Segmentation Model.

Abnormalities in adrenal gland size may be associated with various diseases. Monitoring the volume of adrenal gland can provide a quantitative imaging indicator for such conditions as adrenal hyperplasia, adrenal adenoma, and adrenal cortical adenocarcinoma. However, current adrenal gland segmentati...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 1; pp. 47 - 60
Autores principales: Li, Yi, Zhao, Yingnan, Yang, Ping, Li, Caihong, Liu, Liu, Zhao, Xiaofang, Tang, Huali, Mao, Yun
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Feb2025
Acceso en línea:Ver este registro en EBSCOhost
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          Li, Yi
          Zhao, Yingnan
          Yang, Ping
          Li, Caihong
          Liu, Liu
          Zhao, Xiaofang
          Tang, Huali
          Mao, Yun
        affil: https://ror.org/033vnzz93 Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, 400016, Chongqing, China
      sug:
        subj:
          Adrenal Glands Physiology
          Deep Learning
          Image Processing, Computer Assisted
          Diagnostic Imaging
          Automation
          Prediction Models
          Human
          Funding Source
          China
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          Female
          Middle Age
          Aged
          Retrospective Panel Studies
          Academic Medical Centers
          Tomography, X-Ray Computed
          Data Analysis Software
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          Chi Square Test
          Fisher's Exact Test
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          Analysis of Variance
          Kruskal-Wallis Test
          Intraclass Correlation Coefficient
          Health Screening
          Monitoring, Physiologic
          Preoperative Care
          Imaging, Three-Dimensional
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Abnormalities in adrenal gland size may be associated with various diseases. Monitoring the volume of adrenal gland can provide a quantitative imaging indicator for such conditions as adrenal hyperplasia, adrenal adenoma, and adrenal cortical adenocarcinoma. However, current adrenal gland segmentation models have notable limitations in sample selection and imaging parameters, particularly the need for more training on low-dose imaging parameters, which limits the generalization ability of the models, restricting their widespread application in routine clinical practice. We developed a fully automated adrenal gland volume quantification and visualization tool based on the no new U-Net (nnU-Net) for the automatic segmentation of deep learning models to address these issues. We established this tool by using a large dataset with multiple parameters, machine types, radiation doses, slice thicknesses, scanning modes, phases, and adrenal gland morphologies to achieve high accuracy and broad adaptability. The tool can meet clinical needs such as screening, monitoring, and preoperative visualization assistance for adrenal gland diseases. Experimental results demonstrate that our model achieves an overall dice coefficient of 0.88 on all images and 0.87 on low-dose CT scans. Compared to other deep learning models and nnU-Net model tools, our model exhibits higher accuracy and broader adaptability in adrenal gland segmentation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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