Social isolation and poor mental health in young people: testing genetic and environmental influences in a longitudinal cohort study.

We assessed genetic and environmental influences on social isolation across childhood and the overlap between social isolation and mental health symptoms including depression symptoms, conduct problems, and psychotic-like experiences from adolescence to young adulthood. Participants included 2,232 c...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 4; pp. 1445 - 1456
Autores principales: Thompson, Katherine N., Oginni, Olakunle, Wertz, Jasmin, Danese, Andrea, Okundi, Malaika, Arseneault, Louise, Matthews, Timothy
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
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      pub: Springer Nature
      place: New York, New York
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        atl: Social isolation and poor mental health in young people: testing genetic and environmental influences in a longitudinal cohort study.
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          Thompson, Katherine N.
          Oginni, Olakunle
          Wertz, Jasmin
          Danese, Andrea
          Okundi, Malaika
          Arseneault, Louise
          Matthews, Timothy
        affil: https://ror.org/02dqehb95 Department of Sociology, College of Liberal Arts, Purdue University, West Lafayette, IN, United States of America
      sug:
        subj:
          Social Isolation Evaluation
          Mental Health Evaluation
          Genetic Screening
          Depression
          Child Behavior
          Adolescent Behavior
          Psychotic Disorders
          Human
          Child
          Adolescence
          Male
          Female
          Descriptive Statistics
          Funding Source
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: We assessed genetic and environmental influences on social isolation across childhood and the overlap between social isolation and mental health symptoms including depression symptoms, conduct problems, and psychotic-like experiences from adolescence to young adulthood. Participants included 2,232 children from the Environmental Risk Longitudinal Twin Study. Social isolation was measured at ages 5, 7, 10, 12, and 18. A Cholesky decomposition was specified to estimate the genetic and environmental influences on social isolation across ages 5, 7, 10, and 12. An independent pathway model was used to assess additive genetic (A), shared environmental (C), and non-shared environmental (E) influences on the overlap between social isolation and mental health problems from age 12 to 18. Genetic and non-shared environmental influences accounted for half of the variance in childhood social isolation. Genetic influences contributed to the continuity of social isolation across childhood, while non-shared environmental influences were age-specific. The longitudinal overlap between social isolation and mental health symptoms was largely explained by genetic influences for depression symptoms (r = 0.15–0.24: 82–84% A, 11–12% C, and 5–6% E) and psychotic-like experiences (r = 0.13–0.15: 81–91% A, 0–8% C, and 9–11% E) but not conduct problems (r = 0.13–0.16; 0–42% A, 42–81% C, 16–24% E). Our findings emphasise that rather than a risk factor or an outcome, social isolation is aetiologically intertwined with the experience of poor mental health. An integrative assessment of social isolation could be a helpful indicator of underlying mental health symptoms in young people.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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