Prevalence of mental disorders among family members of individuals on the autism spectrum: systematic review and meta-analysis.

Parenting a child on the autism spectrum presents particular challenges that can lead to increased stress, anxiety, and depression among family members. Therefore, we aimed to investigate the prevalence of mental disorders in first-degree relatives of individuals on the autism spectrum. This article...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 4; pp. 1267 - 1280
Autores principales: Lins-Silva, Daniel H., Bandeira, Igor D., Faria-Guimarães, Daniela, Dorea-Bandeira, Ingrid, Tolentino, Arthur, Miranda-Scippa, Ângela, Hermens, Daniel F., Lucena, Rita
Formato: meta analysis research systematic review Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Prevalence of mental disorders among family members of individuals on the autism spectrum: systematic review and meta-analysis.
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          Lins-Silva, Daniel H.
          Bandeira, Igor D.
          Faria-Guimarães, Daniela
          Dorea-Bandeira, Ingrid
          Tolentino, Arthur
          Miranda-Scippa, Ângela
          Hermens, Daniel F.
          Lucena, Rita
        affil: https://ror.org/03k3p7647 Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil
      sug:
        subj:
          Autism Spectrum Disorder Complications
          Parents of Children with Disabilities Psychosocial Factors
          Mental Disorders Epidemiology
          Mental Disorders Risk Factors
          Sibling Relations
          Parent-Child Relations
          Risk Assessment
          Human
          Systematic Review
          Meta Analysis
          Prevalence
          Brazil
          PubMed
          Medline
          Embase
          Psycinfo
          Stress, Psychological Risk Factors
          Anxiety Risk Factors
          Depression Risk Factors
          Odds Ratio
          Confidence Intervals
          Family Attitudes
          Family Coping
          Maternal Attitudes
      ab: Parenting a child on the autism spectrum presents particular challenges that can lead to increased stress, anxiety, and depression among family members. Therefore, we aimed to investigate the prevalence of mental disorders in first-degree relatives of individuals on the autism spectrum. This article adheres to the Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols (PRISMA-P) guidelines, including studies indexed in PubMed/Medline, Embase, PsycINFO, Biblioteca Virtual em Saúde (BVS), and SciELO. Nineteen articles met eligibility criteria for the systematic review. Using a random-effects model (N = 93,876), we found a pooled prevalence of affective disorders of 13% in mothers of people on the autism spectrum (95% CI 7–21%; I2 = 99%, p < 0.01). Additionally, another random-effects model pointed out that first-degree relatives of people on the autism spectrum (N = 93,263) were more likely to present affective disorders than relatives of people with neurotypical development (N = 152,455) (pooled OR: 2.17; 95% CI 1.81–2.61). Careful assessment for mental disorders in parents and siblings of individuals on the autism spectrum is crucial to ensure appropriate treatment for these family members. This approach can also contribute to optimizing care for the individuals on the autism spectrum.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        Journal Article
      ougenre: Article
    language: English
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