Rapid response systems, antibiotic stewardship and medication reconciliation: a scoping review on implementation factors, activities and outcomes.

Introduction Many patient safety practices are only partly established in routine clinical care, despite extensive quality improvement efforts. Implementation science can offer insights into how patient safety practices can be successfully adopted. Objective The objective was to examine the literatu...

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Publicado en:BMJ Quality & Safety Vol. 34; no. 4; pp. 257 - 269
Autores principales: Ohlsen, Jonas Torp, Søfteland, Eirik, Akselsen, Per Espen, Assmus, Jörg, Harthug, Stig, Lein, Regina Küfner, Sevdalis, Nick, Wæhle, Hilde Valen, Øvretveit, John, Hartveit, Miriam
Formato: research systematic review tables/charts Journal Article
Publicado: BMJ Publishing Group Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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        10.1136/bmjqs-2024-017185
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        atl: Rapid response systems, antibiotic stewardship and medication reconciliation: a scoping review on implementation factors, activities and outcomes.
      aug:
        au:
          Ohlsen, Jonas Torp
          Søfteland, Eirik
          Akselsen, Per Espen
          Assmus, Jörg
          Harthug, Stig
          Lein, Regina Küfner
          Sevdalis, Nick
          Wæhle, Hilde Valen
          Øvretveit, John
          Hartveit, Miriam
        affil: Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway
      sug:
        subj:
          Rapid Response (Emergency Care)
          Antimicrobial Stewardship
          Medication Reconciliation
          Patient Safety
          Human
          Scoping Review
          Medline
          Embase
          CINAHL Database
          Psycinfo
          Quality Improvement
          Implementation Science
          Funding Source
      ab: Introduction Many patient safety practices are only partly established in routine clinical care, despite extensive quality improvement efforts. Implementation science can offer insights into how patient safety practices can be successfully adopted. Objective The objective was to examine the literature on implementation of three internationally used safety practices: medication reconciliation, antibiotic stewardship programmes and rapid response systems. We sought to identify the implementation activities, factors and outcomes reported; the combinations of factors and activities supporting successful implementation; and the implications of the current evidence base for future implementation and research. Methods We searched Medline, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature, PsycINFO and Education Resources Information Center from January 2011 to March 2023. We included original peer-reviewed research studies or quality improvement reports. We used an iterative, inductive approach to thematically categorise data. Descriptive statistics and hierarchical cluster analyses were performed. Results From the 159 included studies, eight categories of implementation activities were identified: education; planning and preparation; method-based approach; audit and feedback; motivate and remind; resource allocation; simulation and training; and patient involvement. Most studies reported activities from multiple categories. Implementation factors included: clinical competence and collaboration; resources; readiness and engagement; external influence; organisational involvement; QI competence; and feasibility of innovation. Factors were often suggested post hoc and seldom used to guide the selection of implementation strategies. Implementation outcomes were reported as: fidelity or compliance; proxy indicator for fidelity; sustainability; acceptability; and spread. Most studies reported implementation improvement, hindering discrimination between more or less important factors and activities. Conclusions The multiple activities employed to implement patient safety practices reflect mainly method-based improvement science, and to a lesser degree determinant frameworks from implementation science. There seems to be an unexploited potential for continuous adaptation of implementation activities to address changing contexts. Research-informed guidance on how to make such adaptations could advance implementation in practice.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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