tDCS Combined with CIMT for Post-stroke Upper Extremity Rehabilitation: A Systematic Review and Meta-Analysis.

Background: Transcranial direct current stimulation (tDCS) has been widely used as an adjunctive treatment for motor function after stroke. Objective: To quantify the effect of tDCS combined with constraint-induced movement therapy (CIMT) on the functional recovery of the upper limb after stroke. Me...

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Publicado en:NeuroRehabilitation Vol. 56; no. 2; pp. 97 - 113
Autores principales: Jiang, Tao, Yan, Jiamin, Li, Xiaohan, Yang, Minguang, Zhuang, Yueyang, Ding, Zhimin, Tan, Mengquan, Xia, Sijia, Li, Rui, Wang, Wenju, Chen, Feng, Xie, Xi, Liu, Weilin
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Sage Publications Inc. Mar2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2025
      vid: 56
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: tDCS Combined with CIMT for Post-stroke Upper Extremity Rehabilitation: A Systematic Review and Meta-Analysis.
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          Jiang, Tao
          Yan, Jiamin
          Li, Xiaohan
          Yang, Minguang
          Zhuang, Yueyang
          Ding, Zhimin
          Tan, Mengquan
          Xia, Sijia
          Li, Rui
          Wang, Wenju
          Chen, Feng
          Xie, Xi
          Liu, Weilin
        affil: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China
      sug:
        subj:
          Transcranial Direct Current Stimulation
          Constraint-Induced Therapy
          Upper Extremity
          Rehabilitation
          Functional Status
          Recovery
          Stroke
          Treatment Outcomes
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Systematic Review
          Meta Analysis
          PubMed
          Embase
          Cochrane Library
          Combined Modality Therapy
          Motor Activity
          Neurotransmitters
          Physical Therapy
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Transcranial direct current stimulation (tDCS) has been widely used as an adjunctive treatment for motor function after stroke. Objective: To quantify the effect of tDCS combined with constraint-induced movement therapy (CIMT) on the functional recovery of the upper limb after stroke. Methods: By May 2024, two independent authors screened relevant randomized controlled trials (RCTs) published in English from PubMed, Embase, Web of Science and the Cochrane Library. Publication bias was assessed using the Egger's test. Results: Of the 221 retrieved records, seven publications met the criteria for systematic review and quantitative analysis. According to estimates of Hedges'g, significant effects were revealed from Fugl-Meyer Assessment for Upper Limbs (UL-FMA) for upper limb impairment (g = 0.587, 95% CI = 0.256 to 0.919, p < 0.05) and Motor Activity Log-Amount of Movement (MAL-AoM) for perceived amount of motor (g = 0.386, 95% CI = 0.030 to 0.743, p < 0.05). Significant results favoring combined therapy were not found in Motor Activity Log-Quality of Movement (MAL-QoM) (g = 0.181, 95% CI = −0.169 to 0.531, p > 0.05), grip strength (g = 0.135, 95% CI = -0.214 to 0.485, p > 0.05) or Wolf Motor Function Test (WMFT) (g = 0.210, 95% CI = −0.117 to 0.537, p > 0.05). Conclusions: Our findings confirmed that tDCS enhanced the effect of CIMT in improving upper limb impairment and perceived amount of motor in daily life after stroke.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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