Assessing Frontal Lobe Function on Verbal Fluency and Emotion Recall in Autism Spectrum Disorder by fNIRS.
This study applied the functional near-infrared spectroscopy (fNIRS) to investigate frontal activity in autism when performing verbal fluency test and emotion recall task. We recruited 32 autistic adults without intellectual disability and 30 typically-developing controls (TDC). Prefrontal hemodynam...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 55; no. 5; pp. 1648 - 1660 |
|---|---|
| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184706137&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184706137 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: May2025 vid: 55 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 184706137 176665119 184706137 184706137 10.1007/s10803-024-06306-5 184706137 ppf: 1648 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Assessing Frontal Lobe Function on Verbal Fluency and Emotion Recall in Autism Spectrum Disorder by fNIRS. aug: au: Chien, Yi-Ling Tseng, Yi-Li Tsai, Wen-Che Chiu, Yen-Nan affil: https://ror.org/03nteze27 Department of Psychiatry, National Taiwan University Hospital & College of Medicine, Taipei, Taiwan sug: subj: Autism Spectrum Disorder Psychosocial Factors Frontal Lobe Physiology Verbal Behavior Language Tests Emotions Spectroscopy, Near-Infrared Task Performance and Analysis Human Adult Male Female Funding Source Comparative Studies Brain Physiology Social Behavior Cognition Evaluation Adult: 19-44 years Male Female ab: This study applied the functional near-infrared spectroscopy (fNIRS) to investigate frontal activity in autism when performing verbal fluency test and emotion recall task. We recruited 32 autistic adults without intellectual disability and 30 typically-developing controls (TDC). Prefrontal hemodynamic changes were evaluated by fNIRS when the participants performed the verbal fluency test and emotion recall task. fNIRS signals in the prefrontal cortex were compared between autism and TDC. Compared to TDC, autistic adults showed comparable performance on the verbal fluency test but exhibited lower frontal activity on the vegetable category. In the verbal fluency test, left frontal activity in TDC significantly increased in the vegetable category (vs. fruit category). In the emotion recall task, left frontal activity increased significantly in TDC when recalling emotional (vs. neutral) events. This increase of left frontal activity on the more difficult works was not found in autism. Similarly, brain activities were related to test performance only in TDC but not in autism. In addition, more severe social deficits were associated with lower frontal activity when recalling emotional events, independent of autism diagnosis. Findings suggested reduced frontal activity in autism, as compared to TDC, when performing verbal fluency tests. The reduction of left frontal activation in verbal fluency test and emotion recall tasks might reflect on the social deficits of the individual. The fNIRS may potentially be applied in assessing frontal lobe function in autism and social deficits in general population. Trial registration number: NCT04010409. Lay Summary: Cognitively able autistic adults showed lower prefrontal activation than non-autistic people on the verbal fluency task that assesses executive function. Although higher cognitive load typically triggers stronger prefrontal activity in verbal fluency and emotion recall tasks, this task-difficulty effect was not found in autistic adults. In addition, more severe social deficits were independently associated with lower frontal activity when recalling emotional events, implying a potential utility of the fNIRS in assessing frontal lobe function in autism and for social deficits in general population. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|