Early-Day Protein Intake Influences the Transition of Metabolic Health Phenotypes among Adults with Obesity.
Metabolically healthy obesity (MHO) represents a subset of obesity characterized by a lower risk of cardiometabolic syndrome than individuals with metabolically unhealthy obesity (MUO). This study aimed to (1) describe the transition of metabolic health phenotypes in adults with obesity and (2) iden...
| Publicado en: | Current Research in Nutrition & Food Science Vol. 12; no. 3; pp. 1261 - 1272 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Current Research in Nutrition & Food Science
Dec2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184740728&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184740728 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2347467X KIVQ jtl: Current Research in Nutrition & Food Science issn: 2347467X maglogo: N pubinfo: dt: Dec2024 vid: 12 iid: 3 pid: 25572 pub: Current Research in Nutrition & Food Science artinfo: ui: 184740728 184740728 184740728 10.12944/CRNFSJ.12.3.22 184740728 ppf: 1261 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Early-Day Protein Intake Influences the Transition of Metabolic Health Phenotypes among Adults with Obesity. aug: au: MAZRI, FATIN HANANI TI MEI JUN ABDULLAH AL-MASWARY, ANAS AHMED KANNAN, DIVAASHNI ABDUL LATIF, NURUL HAZIMAH RAMACHANDRAN, JOSEFINA MOHD KERI, FATIN UMAIRAH BESAISO, MARAM MANAF, ZAHARA ABDUL affil: Faculty of Health Sciences, Dietetic Program and Centre for Healthy Ageing and Wellness, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia sug: subj: Phenotype Obesity Psychosocial Factors Dietary Proteins Energy Intake Weight Reduction Programs Human Secondary Analysis Cross Sectional Studies Data Analysis Software Descriptive Statistics Chi Square Test Fisher's Exact Test One-Way Analysis of Variance Male Female Adult Middle Age Sociodemographic Factors Malaysia Body Mass Index Cardiometabolic Risk Factors Quasi-Experimental Studies Funding Source Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Metabolically healthy obesity (MHO) represents a subset of obesity characterized by a lower risk of cardiometabolic syndrome than individuals with metabolically unhealthy obesity (MUO). This study aimed to (1) describe the transition of metabolic health phenotypes in adults with obesity and (2) identify the differentiating factors associated with this transition following the 12-week weight reduction program. This study recruited 91 adults with obesity (Age: 39.6±6.3 years; 74.7% women; body mass index (BMI): 31.2±4.5 kg/m2). The weight reduction intervention incorporates multiple lifestyle domains, including dietary modifications, physical activity, behavioural strategies, and chrono-nutrition, which encompasses temporal eating patterns, meal timing and sleep. At pre-intervention, 55% of participants (n=50) were classified as MHO: BMI=25kg/m2 with fewer than three metabolic abnormalities, while 45% (n=41) were classified as MUO: BMI=25kg/m2 with three or more metabolic abnormalities. Post-intervention, about 24% of the participants (n=22) exhibited positive changes, transitioning from MUO to MHO or from MUO/MHO to metabolically healthy normal weight (MHN). The MUO proportion decreased to 31% (n=28), and 45% (n=41) remained as MHO. Participants who demonstrated positive changes were characterized with highest increase in energy intake from protein sources (+5.2% vs +1.1%, p=0.004), particularly during the earlier part of the day (+4.3% vs +1.1%, p=0.029), greater body weight loss (-7.0% vs -3.2%, p=0.022), body fat loss (-3.4% vs -1.3%, p=0.013) and visceral fat loss (-1.3 vs -0.5, p=0.013) as well as a higher proportion of morning chronotype (72.7% vs 35.7%, p=0.033), than the participants who showed negative changes. These results imply that, the timing of protein intake and chronotype may play significant roles in mitigating the risk of cardiometabolic syndrome among adults with obesity, in addition to weight reduction. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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