Substance Use Classes Among YMSM in an HIV Digital Health Intervention Program: Implications for Acceptability, Engagement, and Health Outcomes.

Young men who have sex with men (YMSM) have high rates of substance use, which increases their risk for HIV. Digital Health Interventions (DHI) have the potential to address HIV risk overall and reduce harms in the context of substance use. However, there is limited research on how YMSM with differe...

Descripción completa

Detalles Bibliográficos
Publicado en:AIDS & Behavior Vol. 29; no. 5; pp. 1479 - 1492
Autores principales: Zapata, Juan Pablo, Swann, Gregory, Zamantakis, Alithia, Madkins, Krystal, Danielson, Elizabeth Caitlin Anne, Mustanski, Brian
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184744519&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 184744519
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10907165
        G1T
      jtl: AIDS & Behavior
      issn: 10907165
      maglogo: N
    pubinfo:
      dt: May2025
      vid: 29
      iid: 5
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        184744519
        182431486
        184744519
        184744519
        10.1007/s10461-025-04619-9
        184744519
      ppf: 1479
      ppct: 13
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Substance Use Classes Among YMSM in an HIV Digital Health Intervention Program: Implications for Acceptability, Engagement, and Health Outcomes.
      aug:
        au:
          Zapata, Juan Pablo
          Swann, Gregory
          Zamantakis, Alithia
          Madkins, Krystal
          Danielson, Elizabeth Caitlin Anne
          Mustanski, Brian
        affil: https://ror.org/000e0be47 Institute for Sexual and Gender Minority Health and Wellbeing, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
      sug:
        subj:
          Substance Use Disorders Classification
          Men Who Have Sex With Men In Adolescence
          Digital Health
          Program Evaluation
          HIV Infections Prevention and Control
          Outcomes (Health Care)
          Sexually Transmitted Diseases
          Human
          Funding Source
          Adolescence
          Descriptive Statistics
          Structural Equation Modeling
          Telehealth
          Adolescent: 13-18 years
      ab: Young men who have sex with men (YMSM) have high rates of substance use, which increases their risk for HIV. Digital Health Interventions (DHI) have the potential to address HIV risk overall and reduce harms in the context of substance use. However, there is limited research on how YMSM with different substance use patterns respond to HIV DHIs and how these programs impact participant outcomes. In this study, we used latent class analysis (LCA) to identify subgroups of participants with specific substance use behaviors in the Keep It Up! (KIU!) program, an HIV DHI with prior documented effectiveness. This study involved 2,124 participants in a Type III Hybrid trial, comparing two implementation strategies: one via 22 community-based organizations and another through direct-to-consumer recruitment. Evaluations were done at baseline and 12-week follow-up. This analysis identified four classes of substance use: Low Use (minimal alcohol risks, low illicit drug use, infrequent marijuana), Heavy Use (highest alcohol problems, frequent marijuana, elevated illicit drug use), Alcohol and Marijuana Use (high alcohol problems, frequent marijuana), and Methamphetamine and GBH Use (low alcohol risk, moderate marijuana frequency, high illicit drug use). Participants in the Meth & GHB User class were more likely to have an STI at baseline compared to those in the Low User class. Moreover, Heavy Use, Alcohol & Marijuana Use, and Meth & GHB Use reported a greater number of condomless anal sex partners compared to Low Use. Additionally, although Alcohol & Marijuana Use were more likely to use PrEP at the time of their most recent casual partner at baseline, they exhibited the smallest increase in PrEP use during follow-up compared to the other substance use classes. Our analysis did not unveil substantial differences in the success of implementation in terms of reach, suggesting that both implementation strategies effectively engaged YMSM with different levels of substance use. Our research showed a similar level of engagement, as evidenced by the completion rates of modules and time spent, across all substance use classes. However, those within the Meth & GHB category found the intervention highly acceptable, but less so compared to Low Use and Alcohol & Marijuana Use. Understanding how distinct substance use profiles influence intervention outcomes and exploring varied implementation methods can augment future prevention endeavors, broadening the scope and impact of public health initiatives.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N