Predicting Trajectories of Everyday Functioning in Adults Aging with HIV Using Latent Growth Mixture Modeling.
As the U.S. population of people with HIV (PWH) ages, PWH exhibit high rates of adverse health outcomes including everyday functioning decline. We aimed to (1) identify trajectories of self-reported everyday functioning and (2) examine baseline predictors (demographics, cognitive domains, psychiatri...
| Publicado en: | AIDS & Behavior Vol. 29; no. 5; pp. 1525 - 1540 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184744523&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184744523 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: May2025 vid: 29 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 184744523 182898869 184744523 184744523 10.1007/s10461-025-04623-z 184744523 ppf: 1525 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Predicting Trajectories of Everyday Functioning in Adults Aging with HIV Using Latent Growth Mixture Modeling. aug: au: Ham, Lillian Roesch, Scott Franklin, Donald R. Ellis, Ronald J. Grant, Igor Moore, David J. affil: San Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, USA sug: subj: Activities of Daily Living In Adulthood Aging HIV-Positive Persons Predictive Research Cognition HIV Infections Comorbidity Human Funding Source United States Male Female Adult Models, Statistical Prospective Studies Questionnaires Neuropsychological Tests Enzyme-Linked Immunosorbent Assay Blotting, Western Self Report Hepatitis C Hypertension Descriptive Statistics Chi Square Test Adult: 19-44 years Male Female ab: As the U.S. population of people with HIV (PWH) ages, PWH exhibit high rates of adverse health outcomes including everyday functioning decline. We aimed to (1) identify trajectories of self-reported everyday functioning and (2) examine baseline predictors (demographics, cognitive domains, psychiatric and medical comorbidities, HIV-disease characteristics) of trajectories among PWH. 742 PWH completed up to five semi-annual visits over two years. Latent growth mixture modeling identified a linear 3-class solution with good statistical fit and interpretability. Most PWH (88%) had good baseline functioning with stability. Two classes had elevated baseline functional declines with worsening (7%) or improvement (5%). Greater depressive symptoms and motor skills impairment predicted higher odds of impaired functioning. Having chronic pulmonary disease increased odds of improvement, which may reflect connection to care, while older age increased odds of worsening. Most aging PWH demonstrate stable everyday functioning; however, interventions for depression and motor skills may improve functioning. Resumen: A medida que la población de individuos con VIH en Estados Unidos envejece, sus riesgos de salud aumentan, incluyendo la capacidad de realizar actividades de la vida diaria (AVD). Nuestros objetivos fueron (1) identificar trayectorias de capacidad para realizar AVD en individuos con VIH y (2) examinar características (información demográfica, capacidad cognitiva, enfermedades y características de VIH) que puedan predecir estas trayectorias. 742 participantes con VIH completaron hasta cinco visitas semestrales durante 2 años. Un modelo de curva de crecimiento mixto latente identificó una solución lineal de 3 clases con buen ajuste estadístico e interpretabilidad. En la mayoría de los participantes (88%) se observó buen y estable funcionamiento diario al principio del estudio. En dos clases (grupos) se encontraron peores disminuciones funcionales con deterioros (7%) o mejoras (5%) subsecuentes. Mayores síntomas depresivos y problemas motrices predijeron mayor probabilidad de impedimentos en AVD. Presencia de enfermedad pulmonar crónica predijo mejor capacidad de realizar AVD, un resultado que quizas refleja acceso a atención médica. Mayor edad predijo peor capacidad para realizar AVD. La mayoría de la gente envejeciendo con VIH demostró estabilidad en su capacidad de realizar actividades cotidianas. Intervenciones para la depresión y capacidad motriz podrían mejorar el funcionamiento diario. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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