Pre-exposure Prophylaxis (PrEP) Awareness and Engagement Among MSM at High Risk of HIV Infection in China: A Multi-City Cross-Sectional Survey.

This study aimed to explore the awareness, willingness, and engagement with pre-exposure prophylaxis (PrEP) among high-risk Chinese men who have sex with men (MSM) and to investigate the factors influencing its use. A cross-sectional survey of 1800 HIV-negative MSM was conducted in Chengdu, Suzhou,...

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Publicado en:AIDS & Behavior Vol. 29; no. 5; pp. 1629 - 1640
Autores principales: Du, Jun, Wang, Sainan, Zhang, Hongbo, Liu, Tao, Sun, Shufang, Yang, Cui, Zaller, Nickolas, Dai, Zhen, Zha, Haipeng, Zhao, Yanqiu, Zhao, Yue, Hu, Xuejiao, Yan, Han, Gao, Pan, Wang, Jun, Sun, Yehuan, Zhang, Zhihua, Don, Operario
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Pre-exposure Prophylaxis (PrEP) Awareness and Engagement Among MSM at High Risk of HIV Infection in China: A Multi-City Cross-Sectional Survey.
      aug:
        au:
          Du, Jun
          Wang, Sainan
          Zhang, Hongbo
          Liu, Tao
          Sun, Shufang
          Yang, Cui
          Zaller, Nickolas
          Dai, Zhen
          Zha, Haipeng
          Zhao, Yanqiu
          Zhao, Yue
          Hu, Xuejiao
          Yan, Han
          Gao, Pan
          Wang, Jun
          Sun, Yehuan
          Zhang, Zhihua
          Don, Operario
        affil: https://ror.org/03xb04968 Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 230032, Hefei, China
      sug:
        subj:
          Men Who Have Sex With Men Psychosocial Factors
          Pre-Exposure Prophylaxis Utilization
          Health Knowledge
          HIV Infections Prevention and Control
          Risk Assessment
          Attitude to Health
          Human
          Multicenter Studies
          Cross Sectional Studies
          Funding Source
          China
          Univariate Statistics
          Multiple Logistic Regression
          Data Analysis Software
          Risk Taking Behavior
          Sexual Partners
          Male
          Health Behavior
          Male
      ab: This study aimed to explore the awareness, willingness, and engagement with pre-exposure prophylaxis (PrEP) among high-risk Chinese men who have sex with men (MSM) and to investigate the factors influencing its use. A cross-sectional survey of 1800 HIV-negative MSM was conducted in Chengdu, Suzhou, and Wuhan between June 2022 and February 2023 through in-person and online recruitment methods. Univariate and multivariate logistic regression analyses were used to identify predictors of PrEP use. Bayesian network models were constructed using the bnlearn package in R 4.1.2, and inference was conducted using Netica software. Among the 1800 participants, 1467 had ever heard of PrEP, 696 were aware of its target population, and 195 had taken PrEP in the past 6 months. PrEP use was higher among individuals reporting multiple male sex partners, illicit substance use, alcohol use, HIV testing, PEP use, and sexual partners who had used PrEP. Conversely, having a female sexual partner was a barrier to PrEP use. Bayesian network modeling unveiled factors directly and indirectly impacting PrEP use. Variables like PrEP use of sexual partners, PEP use, alcohol use, HIV testing, and WeChat-based HIV knowledge platforms exhibited direct effects. Indirect effects included having a female sexual partner, number of male sexual partners, and illicit substance use. Despite high awareness, the usage of PrEP remains low among MSM. Encouraging social agencies to leverage social media platforms to provide comprehensive HIV care services, especially to meet the PrEP needs of MSM.
      pubtype: Academic Journal
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      ougenre: Article
    language: English
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