From population-based to personalized laboratory medicine: continuous monitoring of individual laboratory data with wearable biosensors.
Monitoring individuals' laboratory data is essential for assessing their health status, evaluating the effectiveness of treatments, predicting disease prognosis and detecting subclinical conditions. Currently, monitoring is performed intermittently, measuring serum, plasma, whole blood, urine and oc...
| Publicado en: | Critical Reviews in Clinical Laboratory Sciences Vol. 62; no. 3; pp. 198 - 228 |
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| Autores principales: | , , , |
| Formato: | equations & formulas pictorial review tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
May2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184762741&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184762741 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10408363 1AV jtl: Critical Reviews in Clinical Laboratory Sciences issn: 10408363 maglogo: Y pubinfo: dt: May2025 vid: 62 iid: 3 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 184762741 182599898 184762741 184762741 10.1080/10408363.2025.2453152 184762741 ppf: 198 ppct: 30 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: From population-based to personalized laboratory medicine: continuous monitoring of individual laboratory data with wearable biosensors. aug: au: Coskun, Abdurrahman Savas, Irem Nur Can, Ozge Lippi, Giuseppe affil: Department of Medical Biochemistry, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey sug: subj: Wearable Sensors Biosensing Techniques Methods Diagnosis, Laboratory Monitoring, Physiologic Methods Individualized Medicine Health Status Evaluation Body Fluids Human Body ab: Monitoring individuals' laboratory data is essential for assessing their health status, evaluating the effectiveness of treatments, predicting disease prognosis and detecting subclinical conditions. Currently, monitoring is performed intermittently, measuring serum, plasma, whole blood, urine and occasionally other body fluids at predefined time intervals. The ideal monitoring approach entails continuous measurement of concentration and activity of biomolecules in all body fluids, including solid tissues. This can be achieved through the use of biosensors strategically placed at various locations on the human body where measurements are required for monitoring. High-tech wearable biosensors provide an ideal, noninvasive, and esthetically pleasing solution for monitoring individuals' laboratory data. However, despite significant advances in wearable biosensor technology, the measurement capacities and the number of different analytes that are continuously monitored in patients are not yet at the desired level. In this review, we conducted a literature search and examined: (i) an overview of the background of monitoring for personalized laboratory medicine, (ii) the body fluids and analytes used for monitoring individuals, (iii) the different types of biosensors and methods used for measuring the concentration and activity of biomolecules, and (iv) the statistical algorithms used for personalized data analysis and interpretation in monitoring and evaluation. pubtype: Academic Journal doctype: equations & formulas pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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