Preferences of parents from diverse backgrounds on genomic screening of apparently healthy newborns.

Genomic sequencing has been proposed as a strategy to expand newborn screening. Perspectives on genomic newborn screening from parents of diverse racial, ethnic, and socioeconomic backgrounds are needed to shape equitable implementation of this modality. We conducted 20 semi‐structured interviews (1...

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Publicado en:Journal of Genetic Counseling Vol. 34; no. 2; pp. 1 - 11
Autores principales: Gold, Nina B., Omorodion, Jacklyn O., del Rosario, Maya C., Rivera‐Cruz, Greysha, Hsu, Celeste Y., Ziniel, Sonja I., Holm, Ingrid A.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
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      pub: Wiley-Blackwell
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        atl: Preferences of parents from diverse backgrounds on genomic screening of apparently healthy newborns.
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        au:
          Gold, Nina B.
          Omorodion, Jacklyn O.
          del Rosario, Maya C.
          Rivera‐Cruz, Greysha
          Hsu, Celeste Y.
          Ziniel, Sonja I.
          Holm, Ingrid A.
        affil: Division of Medical Genetics and Metabolism, Massachusetts General Hospital for Children, Boston Massachusetts,, USA
      sug:
        subj:
          Genetic Screening
          Neonatal Assessment
          Parents Psychosocial Factors
          Human
          Male
          Female
          Adolescence
          Adult
          Middle Age
          Infant, Newborn
          Thematic Analysis
          Focus Groups
          Funding Source
          Semi-Structured Interview
          United States
          Audiorecording
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Infant, Newborn: birth-1 month
          Male
          Female
      ab: Genomic sequencing has been proposed as a strategy to expand newborn screening. Perspectives on genomic newborn screening from parents of diverse racial, ethnic, and socioeconomic backgrounds are needed to shape equitable implementation of this modality. We conducted 20 semi‐structured interviews (15 English, 5 Spanish) and seven focus groups (4 English, 3 Spanish) with parents from diverse backgrounds to assess their perspectives regarding which disorders and variants might be screened, data privacy, and barriers to pursuing specialized care. Parents felt that genomic newborn screening would provide them with improved understanding of their children's health and had the potential to yield health and personal benefits. Themes that became evident included: interest in childhood and family health risks, the value of emotional preparation and personal planning, understanding of uncertain and low‐risk results, concerns regarding data privacy, and concerns about support following the receipt of a positive newborn screening result. The expected benefits and concerns expressed by parents of diverse backgrounds regarding genomic newborn screening should guide future policy decisions. Their preferences should be considered prior to the implementation of large‐scale genomic newborn screening programs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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