Pre-treatment and post-treatment nasopharyngeal carcinoma imaging: imaging updates, pearls and pitfalls.

Purpose: Nasopharyngeal carcinoma (NPC) is endemic in Southeast Asia, requiring precise imaging for personalized treatment. This review highlights key imaging challenges and updates from recent literature, emphasizing findings that impact oncological management. Methods: We discuss common and uncomm...

Descripción completa

Detalles Bibliográficos
Publicado en:Neuroradiology Vol. 67; no. 4; pp. 1023 - 1048
Autores principales: Li, Kwok Yan, Kwok, Hoi Ming, Pan, Nin Yuan, Cheng, Lik Fai, Ma, Ka Fai Johnny
Formato: diagnostic images review tables/charts Journal Article
Publicado: Springer Nature Apr2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184825694&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 184825694
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        00283940
        NYZ
      jtl: Neuroradiology
      issn: 00283940
      maglogo: N
    pubinfo:
      dt: Apr2025
      vid: 67
      iid: 4
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        184825694
        184376171
        184825694
        184825694
        10.1007/s00234-025-03596-z
        184825694
      ppf: 1023
      ppct: 25
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Pre-treatment and post-treatment nasopharyngeal carcinoma imaging: imaging updates, pearls and pitfalls.
      aug:
        au:
          Li, Kwok Yan
          Kwok, Hoi Ming
          Pan, Nin Yuan
          Cheng, Lik Fai
          Ma, Ka Fai Johnny
        affil: https://ror.org/03jrxta72 Department of Diagnostic and Interventional Radiology, Princess Margaret Hospital, Hong Kong SAR, China
      sug:
        subj:
          Nasopharyngeal Carcinoma Diagnosis
          Diagnostic Imaging Evaluation
          Nasopharyngeal Carcinoma Therapy
          Signal Processing, Computer Assisted
          Tumor Burden
          Neoplasm Staging
          Diagnosis, Differential
          Hyperplasia Diagnosis
          Osteomyelitis Diagnosis
          Skull Neoplasms Diagnosis
          Lymph Nodes Pathology
          Nasopharyngeal Carcinoma Physiopathology
          Cicatrix Diagnosis
          Recurrence Diagnosis
          Recurrence Risk Factors
          Radiation Injuries Complications
          Necrosis Risk Factors
          Recurrence Surgery
          Endoscopy
      ab: Purpose: Nasopharyngeal carcinoma (NPC) is endemic in Southeast Asia, requiring precise imaging for personalized treatment. This review highlights key imaging challenges and updates from recent literature, emphasizing findings that impact oncological management. Methods: We discuss common and uncommon clinical entities, detailing salient imaging features and diagnostic distinctions to aid accurate interpretation. Results: In the pre-treatment setting, leveraging the characteristic MR signals and spread patterns of NPC aids in defining the tumor volume for accurate staging and radiotherapy contouring. Key diagnostic challenges include differentiating tumor from benign hyperplasia, skull base osteomyelitis, and other skull base tumors. Perineural tumor spread, radiological extranodal extension and nodal necrosis further refine primary tumor and nodal assessment. In the post-treatment setting, the key question is whether tumor recurrence exists. Diagnostic challenges involve distinguishing tumor recurrence from scar tissue, post-radiation nasopharyngeal necrosis, or hypertrophied cervical ganglia. For recurrences, endoscopic nasopharyngectomy has emerged as the preferred approach over open surgery or re-irradiation. The text highlights characteristic post-treatment appearances and emphasizes recognizing these patterns to avoid misinterpretation and guide appropriate management. Conclusion: Imaging plays a pivotal role in NPC precision oncology. Mastering imaging pearls and pitfalls empowers radiologists to provide clinicians with reliable, actionable guidance.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N