Enhancing Malignancy Detection and Tumor Classification in Pathology Reports: A Comparative Evaluation of Large Language Models...19th Health Informatics Meets Digital Health Conference (dHealth), May 6-7, 2025, Vienna, Austria.

Background: Cancer registries require accurate and efficient documentation of malignancies, yet current manual methods are time-consuming and error-prone. Objectives: This study evaluates the effectiveness of large language models (LLMs) in classifying malignancies and detecting tumor types from pat...

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Detalles Bibliográficos
Publicado en:Studies in Health Technology & Informatics Vol. 324; pp. 270 - 276
Autores principales: NEURURER, Sabrina B., TAHA, Hasan, MUEHLBOECK, Helmut, HICKMANN, Christoph, GSCHEIDLINGER, Patricia, RICHTER, Stefan, DANLER, Martin, HACKL, Werner O., UEBEREGGER, Marko, SCHWEITZER, Marco, PFEIFER, Bernhard
Formato: proceedings research tables/charts Journal Article
Publicado: Sage Publications Inc. 2025
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Background: Cancer registries require accurate and efficient documentation of malignancies, yet current manual methods are time-consuming and error-prone. Objectives: This study evaluates the effectiveness of large language models (LLMs) in classifying malignancies and detecting tumor types from pathology reports. Methods: Using a synthetic dataset of 227 reports, the performance of four LLMs and a score-based algorithm was compared against expert-labeled gold standards. Results: The LLMs, particularly GPT-4o and Llama3.3, demonstrated high sensitivity and specificity in both malignancy detection and tumor classification, significantly outperforming traditional algorithms. Conclusion: LLMs enhance the accuracy and efficiency of cancer data classification and hold promise for improving public health monitoring and clinical decision-making.